Postoperative complication's and mortality in older patients having non-cardiac surgery at three Melbourne teaching hospitals

被引:93
作者
McNicol, Larry
Story, David A. [1 ]
Leslie, Kate
Myles, Paul S.
Fink, Michael
Shelton, Andrew C.
Clavisi, Ornella
Poustie, Stephanie J.
机构
[1] Univ Melbourne, Dept Anaesthesia, Melbourne, Vic, Australia
[2] Univ Melbourne, Dept Surg, Melbourne, Vic, Australia
[3] Austin Hlth, Dept Anaesthesia, Melbourne, Vic, Australia
[4] Royal Melbourne Hosp, Dept Anaesthesia & Pain Management, Melbourne, Vic, Australia
[5] Univ Melbourne, Dept Pharmacol, Melbourne, Vic, Australia
[6] Alfred Hosp, Dept Anaesthesia & Perioperat Med, Melbourne, Vic, Australia
[7] Monash Univ, Acad Board Anaesthesia & Perioperat Med, Melbourne, Vic 3004, Australia
[8] Australian & New Zealand Coll Anaesthetists, Trials Grp, Melbourne, Vic, Australia
[9] Monash Univ, Dept Epidemiol & Prevent Med, Melbourne, Vic 3004, Australia
关键词
D O I
10.5694/j.1326-5377.2007.tb00994.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To determine the incidence of postoperative complications, including 30-day mortality rate, and need for intensive care unit (ICU) admission in older patients after non-cardiac surgery. Design and setting: Prospective observational study of all patients aged 70 years or older having elective and non-elective, non-cardiac surgery, and staying at least 1 night after surgery in one of three Melbourne teaching hospitals, June to September 2004. Main outcome measures: Postoperative complications and 30-day mortality rate. Results: 1102 consecutive patients were audited in mid 2004; 70% had pre-existing comorbidities. The 30-day mortality rate was 6%; 19% had postoperative complications; and 20% of patients spent at least 1 night in ICU. On multivariate analysis, preoperative factors associated with 30-day mortality included age (odds ratio [OR], 1.09 per year over 70 years; 95% Cl, 1.04-1.13; P < 0.001); increasing severity of systemic disease (American Society of Anesthesiologists physical status classification) (OR, 2.53; 95% Cl, 1.65-3.86; P < 0.001); and albumin level < 30 g/L (OR, 2.23; 95% Cl, 1.09-4.57; P = 0.03). Postoperative factors associated with 30-day mortality were unplanned ICU admission (OR, 3.95; 95% Cl, 1.63-9.55; P = 0.003); sepsis (OR, 2.75; 95% Cl, 1.17-6.47; P = 0.02); and acute renal impairment (OR, 2.40; 95% Cl, 1.06-5.41; P = 0.04). Thoracic surgery was the only surgical specialty significantly associated with mortality (OR, 3.96; 95% Cl, 1.44-9.10; P = 0.008) in the multivariate analysis. Conclusion: Older patients having surgery had high rates of comorbidities and postoperative complications, placing considerable demands on critical care services. Patient factors were often stronger predictors of mortality than the type of surgery.
引用
收藏
页码:447 / 452
页数:6
相关论文
共 35 条
[1]   The impact of operative complexity on patient risk factors [J].
Aust, JB ;
Henderson, W ;
Khuri, S ;
Page, CP .
ANNALS OF SURGERY, 2005, 241 (06) :1024-1027
[2]   Postoperative serious adverse events in a teaching hospital: a prospective study [J].
Bellomo, R ;
Goldsmith, D ;
Russell, S ;
Uchino, S .
MEDICAL JOURNAL OF AUSTRALIA, 2002, 176 (05) :216-218
[3]   Prospective controlled trial of effect of medical emergency team on postoperative morbidity and mortality rates [J].
Bellomo, R ;
Goldsmith, D ;
Uchino, S ;
Buckmaster, J ;
Hart, G ;
Opdam, H ;
Silvester, W ;
Doolan, L ;
Gutteridge, G .
CRITICAL CARE MEDICINE, 2004, 32 (04) :916-921
[4]   Surgical care in octogenarians [J].
Bufalari, A ;
Ferri, M ;
Cao, P ;
Cirocchi, R ;
Bisacci, R ;
Moggi, L .
BRITISH JOURNAL OF SURGERY, 1996, 83 (12) :1783-1787
[5]   Findings of the First Consensus Conference on Medical Emergency Teams [J].
DeVita, Michael A. ;
Bellomo, Rinaldo ;
Hillman, Kenneth ;
Kellum, John ;
Rotondi, Armando ;
Teres, Dan ;
Auerbach, Andrew ;
Chen, Wen-Jon ;
Duncan, Kathy ;
Kenward, Gary ;
Bell, Max ;
Buist, Michael ;
Chen, Jack ;
Bion, Julian ;
Kirby, Ann ;
Lighthall, Geoff ;
Ovreveit, John ;
Braithwaite, R. Scott ;
Gosbee, John ;
Milbrandt, Eric ;
Peberdy, Mimi ;
Savitz, Lucy ;
Young, Lis ;
Galhotra, Sanjay .
CRITICAL CARE MEDICINE, 2006, 34 (09) :2463-2478
[6]   Outcomes for older patients with hip fractures: The impact of orthopedic and geriatric medicine cocare [J].
Fisher, AA ;
Davis, MW ;
Rubenach, SE ;
Sivakumaran, S ;
Smith, PN ;
Budge, MM .
JOURNAL OF ORTHOPAEDIC TRAUMA, 2006, 20 (03) :172-178
[7]  
FLEISHER LA, 2005, MILLERS ANESTHESIA, P893
[8]   Preoperative serum albumin level as a predictor of operative mortality and morbidity - Results from the national VA surgical risk study [J].
Gibbs, J ;
Cull, W ;
Henderson, W ;
Daley, J ;
Hur, K ;
Khuri, SF .
ARCHIVES OF SURGERY, 1999, 134 (01) :36-42
[9]   Excellent anaesthesia needs patient preparation and postoperative support to influence outcome [J].
Goldhill, David ;
Waldmann, Carl .
CURRENT OPINION IN ANESTHESIOLOGY, 2006, 19 (02) :192-197
[10]   Systemic inflammatory response syndrome and organ dysfunction following gastrointestinal surgery [J].
Haga, Y ;
Beppu, T ;
Doi, K ;
Nozawa, F ;
Mugita, N ;
Ikei, S ;
Ogawa, M .
CRITICAL CARE MEDICINE, 1997, 25 (12) :1994-2000