A Bidirectional Neural Interface Circuit With Active Stimulation Artifact Cancellation and Cross-Channel Common-Mode Noise Suppression

被引：68

作者：

Mendrela, Adam E. ^{[1
]}

Cho, Jihyun ^{[1
]}

Fredenburg, Jeffrey A. ^{[1
]}

Nagaraj, Vivek ^{[2
]}

Netoff, Theoden I. ^{[2
]}

Flynn, Michael P. ^{[1
]}

Yoon, Euisik ^{[1
]}

机构：

[1] Univ Michigan, Dept Elect Engn & Comp Sci, Ann Arbor, MI 48109 USA

[2] Univ Minnesota, Dept Neurosci, Minneapolis, MN 55455 USA

来源：

IEEE JOURNAL OF SOLID-STATE CIRCUITS | 2016年 / 51卷 / 04期

关键词：

Closed-loop stimulation; low power; neural recording; noise cancellation; SAR ADC; MU-W; SOC; EQUALIZATION; PRINCIPLES; EPILEPSY;

D O I：

10.1109/JSSC.2015.2506651

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

This work presents a bidirectional neural interface circuit that enables simultaneous recording and stimulation with a stimulation artifact cancellation circuit. The system employs a common average referencing (CAR) front-end circuit to suppress cross-channel environmental noise to further facilitate use in clinical environment. This paper also introduces a new range-adapting (RA) SAR ADC to lower the system power consumption. A prototype is fabricated in 0.18 mu m CMOS and characterized and tested in vivo in an epileptic rat model. The prototype attenuates stimulation artifacts by up to 42 dB and suppresses cross-channel noise by up to 39.8 dB. The measured power consumption per channel is 330 nW, while the area per channel is 0.17 mm(2).

引用

页码：955 / 965

页数：11

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