Photoacoustic ocular imaging

被引：113

作者：

de la Zerda, Adam ^{[1
,2
,3
]}

Paulus, Yannis M. ^{[4
]}

Teed, Robert ^{[1
,2
]}

Bodapati, Sunil ^{[1
,2
]}

Dollberg, Yosh ^{[5
]}

Khuri-Yakub, Butrus T. ^{[3
]}

Blumenkranz, Mark S. ^{[4
]}

Moshfeghi, Darius M. ^{[4
]}

Gambhir, Sanjiv Sam ^{[1
,2
,6
]}

机构：

[1] Stanford Univ, Mol Imaging Program Stanford, Bio X Program, Palo Alto, CA 94305 USA

[2] Stanford Univ, Dept Radiol, Palo Alto, CA 94305 USA

[3] Stanford Univ, Dept Elect Engn, Palo Alto, CA 94305 USA

[4] Stanford Univ, Dept Ophthalmol, Palo Alto, CA 94305 USA

[5] Act Ventures Grp, Baanana, Israel

[6] Stanford Univ, Dept Bioengn, Palo Alto, CA 94305 USA

来源：

OPTICS LETTERS | 2010年 / 35卷 / 03期

关键词：

HIGH-RESOLUTION; MICROSCOPY;

D O I：

10.1364/OL.35.000270

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We developed a photoacoustic ocular imaging device and demonstrated its utility in imaging the deeper layers of the eye including the retina, choroid, and optic nerve. Using safe laser intensity, the photoacoustic system was able to visualize the blood distribution of an enucleated pig's eye and an eye of a living rabbit. Ultrasound images, which were simultaneously acquired, were overlaid on the photoacoustic images to visualize the eye's anatomy. Such a system may be used in the future for early detection and improved management of neovascular ocular diseases, including wet age-related macular degeneration and proliferative diabetic retinopathy. (C) 2010 Optical Society of America

引用

页码：270 / 272

页数：3

共 12 条

[1]

American National Standards Institute American national standard for the safe use of lasers, 2000, Z13612000 ANSI INC

[2] Carbon nanotubes as photoacoustic molecular imaging agents in living mice [J].