Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant

被引：244

作者：

Valpuesta, V ^{[1
]}

Botella, MA ^{[1
]}

机构：

[1] Univ Malaga, Fac Ciencias, Dept Biol Mol & Bioquim, E-29071 Malaga, Spain

来源：

TRENDS IN PLANT SCIENCE | 2004年 / 9卷 / 12期

关键词：

D O I：

10.1016/j.tplants.2004.10.002

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The biosynthetic pathway of L-ascorbic acid (vitamin C) in plants has been established for several years. However, recent reports describe alternative pathways, revealing a more complex picture of L-ascorbic acid biosynthesis than had been expected. GDP-L-gulose and myo-inositol are proposed as new intermediates in L-ascorbic acid biosynthesis, indicating that part of the animal pathway might also be operating in plants. Enzymatic studies on the GDP-mannose-3',5'-epimerase and L-galactono-1,4-lactone dehydrogenase suggest that they are important regulatory steps for L-ascorbic acid biosynthesis.

引用

收藏

页码：573 / 577

页数：5

相关论文

共 39 条

[1] Engineering increased vitamin C levels in plants by overexpression of a D-galacturonic acid reductase [J].

Agius, F ;

González-Lamothe, R ;

Caballero, JL ;

Muñoz-Blanco, J ;

Botella, MA ;

Valpuesta, V .

NATURE BIOTECHNOLOGY, 2003, 21 (02) :177-181

[2] Ascorbate metabolism and its regulation in animals [J].

Banhegyi, G ;

Braun, L ;

Csala, M ;

Puskas, F ;

Mandl, J .

FREE RADICAL BIOLOGY AND MEDICINE, 1997, 23 (05) :793-803

[3] Ascorbate biosynthesis in mitochondria is linked to the electron transport chain between complexes III and IV [J].

Bartoli, CG ;

Pastori, GM ;

Foyer, CH .

PLANT PHYSIOLOGY, 2000, 123 (01) :335-343

[4] EVOLUTION AND BIOSYNTHESIS OF ASCORBIC-ACID [J].

CHATTERJEE, IB .

SCIENCE, 1973, 182 (4118) :1271-1272

[5] The ascorbic acid redox state controls guard cell signaling and stomatal movement [J].

Chen, Z ;

Gallie, DR .

PLANT CELL, 2004, 16 (05) :1143-1162

[6] Increasing vitamin C content of plants through enhanced ascorbate recycling [J].

Chen, Z ;

Young, TE ;

Ling, J ;

Chang, SC ;

Gallie, DR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (06) :3525-3530

[7] Ascorbic acid, a familiar small molecule intertwined in the response of plants to ozone, pathogens, and the onset of senescence [J].

Conklin, PL ;

Barth, C .

PLANT CELL AND ENVIRONMENT, 2004, 27 (08) :959-970

[8] Genetic evidence for the role of GDP-mannose in plant ascorbic acid (vitamin C) biosynthesis [J].

Conklin, PL ;

Norris, SR ;

Wheeler, GL ;

Williams, EH ;

Smirnoff, N ;

Last, RL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (07) :4198-4203

[9] Ascorbate biosynthesis in Arabidopsis cell suspension culture [J].

Davey, MW ;

Gilot, C ;

Persiau, G ;

Ostergaard, J ;

Han, Y ;

Bauw, GC ;

Van Montagu, MC .

PLANT PHYSIOLOGY, 1999, 121 (02) :535-543

[10]

Davey MW, 2000, J SCI FOOD AGR, V80, P825, DOI [10.1002/(SICI)1097-0010(20000515)80:7&lt

← 1 2 3 4 →