Association Between Dialysis Modalities and Risk of Coronary Artery Disease: A Population-Based Cohort Study in Taiwan

被引：6

作者：

Hung, Yao-Min ^{[1
,3
]}

Chen, Yu-Yen ^{[4
,5
,6
,7
]}

Huang, Wei-Chun ^{[2
]}

Wang, Paul Yung Pou ^{[10
]}

Chou, Pesus ^{[3
]}

Lai, Yun-Ju ^{[4
,8
,9
]}

机构：

[1] Kaohsiung Vet Gen Hosp, Dept Emergency Med, Kaohsiung, Taiwan

[2] Kaohsiung Vet Gen Hosp, Ctr Cardiovasc, Kaohsiung, Taiwan

[3] Natl Yang Ming Univ, Sch Med, Inst Publ Hlth, Taipei, Taiwan

[4] Natl Yang Ming Univ, Sch Med, Taipei, Taiwan

[5] Natl Yang Ming Univ, Community Med Res Ctr, Taipei, Taiwan

[6] Natl Yang Ming Univ, Inst Publ Hlth, Taipei, Taiwan

[7] Natl Yang Ming Univ Hosp, Dept Ophthalmol, Yilan, Taiwan

[8] Taichung Vet Gen Hosp, Puli Branch, Dept Internal Med, Div Endocrinol & Metab, 1 Rongguang Rd, Puli Township 545, Nantou, Taiwan

[9] Natl Taiwan Univ Sport, Dept Exercise Hlth Sci, Taichung, Taiwan

[10] Kaiser Permanente, Div Nephrol, Baldwin Pk, CA USA

来源：

THERAPEUTIC APHERESIS AND DIALYSIS | 2018年 / 22卷 / 05期

关键词：

Coronary artery diseases; End-stage renal disease; Hemodialysis; Peritoneal dialysis; STAGE RENAL-DISEASE; CHRONIC KIDNEY-DISEASE; C-REACTIVE PROTEIN; CARDIOVASCULAR-DISEASE; HEMODIALYSIS-PATIENTS; ESRD PATIENTS; VASCULAR CALCIFICATION; PERITONEAL-DIALYSIS; POSITION STATEMENT; HEALTH-INSURANCE;

D O I：

10.1111/1744-9987.12676

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The hemodynamic effects of hemodialysis (HD) and peritoneal dialysis (PD) on end-stage renal disease (ESRD) patients differ. The influence of dialysis modalities on the cardiovascular system has not been well investigated. We aimed to evaluate the association between dialysis modalities and risk of coronary artery disease (CAD) by using the claim data of Taiwan's Longitudinal Health Insurance Database. This study followed up a cohort of 1624 new onset ESRD patients (18years old), who had started renal replacement therapy during 2000 to 2010; and was followed until 2012. After adjusting for potential confounders, patients who underwent HD had significantly higher risks of incidence of CAD, in comparison with patients who underwent PD (adjusted hazard ratio=1.47; 95% confidence interval=1.01-2.11). An increased risk of incident CAD was distinguished in patients receiving HD, compared with those on PD. Further studies are warranted to explore the underlying mechanism and improve dialysis outcomes.

引用

页码：469 / 475

页数：7

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