Three New Triterpenoids Containing Four-Membered Ring from the Fruiting Body of Ganoderma sinense

被引：47

作者：

Wang, Cui-Fang ^{[1
,2
]}

Liu, Jie-Qing ^{[1
]}

Yan, Yu-Xin ^{[1
,2
]}

Chen, Jian-Chao ^{[1
,2
]}

Lu, Yang ^{[3
]}

Guo, Yong-Hui ^{[3
]}

Qiu, Ming-Hua ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

[2] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China

[3] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 08期

关键词：

LUCIDUM; CYTOTOXICITY; SPORES;

D O I：

10.1021/ol100062b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methyl ganosinensate A (1), ganosinensic acid A (1a), and ganosinensic acid B (2), three new triterpenoids with an unusual four-membered ring skeleton produced by a bond across C-1 to C-11, were isolated from the fruiting body of Ganoderma sinense. Their structures were established on the basis of extensive spectroscopic methods, including 1D and 2D NMR techniques, and methyl ganosinensate A was confirmed by X-ray crystallographic analysis.

引用

页码：1656 / 1659

页数：4

共 12 条

[1]

Chen R Y, 1990, Yao Xue Xue Bao, V25, P940

[2] Anti-HIV-1 protease activity of lanostane triterpenes from the Vietnamese mushroom Ganoderma colossum [J].

El Dine, Riham Salah ;

El Halawany, Ali M. ;

Ma, Chao-Mei ;

Hattori, Masao .

JOURNAL OF NATURAL PRODUCTS, 2008, 71 (06) :1022-1026

[3] New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells [J].

Gao, JJ ;

Min, BS ;

Ahn, EM ;

Nakamura, N ;

Lee, HK ;

Hattori, M .

CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, 50 (06) :837-840

[4] Lucidenic acids P and Q, methyl lucidenate P, and other triterpenoids from the fungus Ganoderma lucidum and their inhibitory effects on Epstein-Barr virus activation [J].

Iwatsuki, K ;

Akihisa, T ;

Tokuda, H ;

Ukiya, M ;

Oshikubo, M ;

Kimura, Y ;

Asano, T ;

Nomura, A ;

Nishino, H .

JOURNAL OF NATURAL PRODUCTS, 2003, 66 (12) :1582-1585

[5] Antiinflammatory triterpenoids and steroids from Ganoderma lucidum and G. tsugae [J].

Ko, Horng-Huey ;

Hung, Chi-Feng ;

Wang, Jih-Pyang ;

Lin, Chun-Nan .

PHYTOCHEMISTRY, 2008, 69 (01) :234-239

[6] Novel cytostatic lanostanoid triterpenes from Ganoderma australe [J].

León, F ;

Valencia, M ;

Rivera, A ;

Nieto, I ;

Quintana, J ;

Estévez, F ;

Bermejo, J .

HELVETICA CHIMICA ACTA, 2003, 86 (09) :3088-3095

[7] The anti-androgen effect of ganoderol B isolated from the fruiting body of Ganoderma lucidum [J].

Liu, Jie ;

Shimizu, Kuniyoshi ;

Konishi, Fumiko ;

Kumamoto, Shoichiro ;

Kondo, Ryuichiro .

BIOORGANIC & MEDICINAL CHEMISTRY, 2007, 15 (14) :4966-4972

[8]

Min BS, 1998, CHEM PHARM BULL, V46, P1607, DOI 10.1248/cpb.46.1607

[9]

Min BS, 2000, CHEM PHARM BULL, V48, P1026

[10] NEW BITTER C-27 AND C-30 TERPENOIDS FROM THE FUNGUS GANODERMA-LUCIDUM (REISHI) [J].

NISHITOBA, T ;

SATO, H ;

KASAI, T ;

KAWAGISHI, H ;

SAKAMURA, S .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1985, 49 (06) :1793-1798

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