An efficient monitoring technique for solid-phase reactions by KBr pellets/FT-IR using methyl p-aminobenzoate synthesis assisted by microwave radiation on Merrifield resin

被引：11

作者：

Antonow, D ^{[1
]}

Graebin, CS ^{[1
]}

Eifler-Lima, VL ^{[1
]}

机构：

[1] Univ Fed Rio Grande do Sul, Fac Farm, BR-90610000 Porto Alegre, RS, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2004年 / 15卷 / 05期

关键词：

Merrifield resin; infrared spectroscopy; solid phase organic synthesis; microwave-assisted reactions;

D O I：

10.1590/S0103-50532004000500028

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The use of KBr pellets in infrared spectroscopy has been investigated for monitoring solid-phase reactions. Synthesis of the methyl p-aminobenzoate on Merrifield resin (MR) is described as a model for this technique, which allows the progress of its three on-bead reaction steps to be monitored throughout their duration.

引用

页码：782 / 785

页数：4

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