Cancer Nucleus: Morphology and Beyond

被引:89
作者
Dey, Pranab [1 ]
机构
[1] Postgrad Inst Med Educ & Res, Dept Cytol, Chandigarh 160012, India
关键词
nucleus; cancer; morphology; POLYMERASE-I TRANSCRIPTION; NEEDLE-ASPIRATION-CYTOLOGY; BREAST EPITHELIAL-CELLS; CHROMATIN TEXTURE; RETINOBLASTOMA PROTEIN; HISTONE DEACETYLASE; MATRIX PROTEINS; IMAGE MORPHOMETRY; PERINUCLEOLAR COMPARTMENT; BIOLOGICAL-CONTROL;
D O I
10.1002/dc.21234
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
There are many significant morphological alterations of a nucleus of cancer cell that are detectable by light microscopy on routine staining. These changes are often associated with deranged cellular functions of cancer cell. It is difficult to understand the exact relationship between nuclear morphology and alteration of nuclear structural organization in cancer. Herein, the salient visual and subvisual morphological changes of cancer nuclei and their possible etiology and significance have been reviewed. Diagn. Cytopathol. 2010;38:382-390. (C) 2009 Wiley-Liss, Inc.
引用
收藏
页码:382 / 390
页数:9
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