Treatment Options in Patients Awaiting Liver Transplantation with Hepatocellular Carcinoma and Cholangiocarcinoma

被引:8
作者
Unzueta, Alberto [1 ]
Cabrera, Roniel [2 ]
机构
[1] Univ Florida, Dept Med, Div Gastroenterol Hepatol & Nutr, 1600 Southwest Archer Rd,POB 100277, Gainesville, FL 32610 USA
[2] Univ Florida, Dept Med, Div Gastroenterol Hepatol & Nutr,Liver Unit, Liver Transplant Program,Sect Hepatobiliary Dis, 1600 Southwest Archer Rd,MSB Room M440, Gainesville, FL 32610 USA
关键词
Locoregional therapies; Bridging; Down-staging; Neoadjuvant therapies; Outcomes; TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; INTENTION-TO-TREAT; PERCUTANEOUS RADIOFREQUENCY ABLATION; LONG-TERM OUTCOMES; TRANSARTERIAL CHEMOEMBOLIZATION; ALPHA-FETOPROTEIN; WAITING-LIST; NEOADJUVANT THERAPY; CIRRHOTIC-PATIENTS; ETHANOL INJECTION;
D O I
10.1016/j.cld.2016.12.002
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Liver transplantation (LT) provides a good chance of cure for selected patients with hepatocellular carcinoma (HCC) and perihilar cholangiocarcinoma (pCCA). Patients with HCC on a waiting list for LT are at risk for tumor progression and dropout. Treatment of HCC with locoregional therapies may lessen dropout due to tumor progression. Strict selection and adherence to the LT criteria for patients with pCCA before and after neo-adjuvant chemotherapy are critical for optimal outcome with LT. This article reviews the existing data for the various treatment strategies used for patients with HCC and pCCA awaiting LT.
引用
收藏
页码:231 / +
页数:22
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