Progressive Multifocal Leukoencephalopathy after Treatment with Nivolumab

被引：33

作者：

Martinot, Martin ^{[1
]}

Ahle, Guido ^{[1
]}

Petrosyan, Inesa ^{[1
]}

Martinez, Camille ^{[1
]}

Gorun, Dragos M. ^{[1
]}

Mohseni-Zadeh, Mahsa ^{[1
]}

Fafi-Kremer, Samira ^{[2
]}

Tebacher-Alt, Martine ^{[2
]}

机构：

[1] Hop Civils Colmar, Colmar, France

[2] Hop Univ Strasbourg, Strasbourg, France

来源：

EMERGING INFECTIOUS DISEASES | 2018年 / 24卷 / 08期

关键词：

INFECTIOUS-DISEASES; IMMUNE; THERAPY; EVENTS; CANCER;

D O I：

10.3201/eid2408.180460

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Progressive multifocal leukoencephalopathy (PML) is increasingly being reported in patients undergoing immunotherapy. We report a case of progressive multifocal leukoencephalopathy after treatment with nivolumab, a PD-1 blocker that is used to restore impaired T-cell responses in patients with cancer and infections. Data for 4 other cases were obtained from pharmacovigilance databases.

引用

收藏

页码：1594 / 1596

页数：3

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