General methodology for synthesis of fused tricyclic oxazino-2-quinolones under phase-transfer catalyzed conditions

被引：14

作者：

Dutta, R

Mandal, D

Panda, N

Mondal, NB

Banerjee, S

Kumar, S

Weber, M

Luger, P

Sahu, NP

机构：

[1] Indian Inst Chem Biol, Kolkata 700032, W Bengal, India

[2] Free Univ Berlin, Inst Chem Crystallog, D-14195 Berlin, Germany

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 51期

关键词：

D O I：

10.1016/j.tetlet.2004.10.134

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot synthesis of substituted oxazino-2-quinolones is described. The cornerstone of this methodology involves PTC catalyzed addition of an ethylene dihalide to a quinol to generate the corresponding O-alkylated intermediate in situ followed by ring closing and subsequent formation of a carbonyl group in the oxazinoquinolone in a one-pot sequence. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：9361 / 9364

页数：4

共 29 条

[1]

[Anonymous], 1997, PHASE TRANSFER CATAL

[2] Stereoselective synthesis of cyclopropane rings under phase-transfer-catalyzed conditions [J].