Longitudinally tracking fluoroquinolone resistance and its determinants in penicillin-susceptible and -nonsusceptible Streptococcus pneumoniae isolates in Hong Kong, 2000 to 2005

被引:22
作者
Ip, Margaret [1 ]
Chau, Shirley S. L. [1 ]
Chi, Fang [1 ]
Cheuk, Edmund S. C. [1 ]
Ma, Helen [1 ]
Lai, Raymond W. M. [1 ]
Chan, Paul K. [1 ]
机构
[1] Chinese Univ Hong Kong, Prince Wales Hosp, Dept Microbiol, Hong Kong, Hong Kong, Peoples R China
关键词
D O I
10.1128/AAC.00139-07
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Of 1,388 Streptococcus pneumoniae isolates collected from 2000 to 2005, 10.5% had a ciprofloxacin MIC of >= 4.0 mu g/ml and 1.6% (range, 0.8% to 4.3% per year) had a levofloxacin MIC of >= 4.0 mu g/ml. Molecular characterization indicated that fluoroquinolone resistance occurred independently in our prevalent Spain(23F)-1 clone, expressing serotypes 23F, 19F, and 14. Rates of resistance to levofloxacin in S. pneumoniae have remained stable at a Hong Kong hospital.
引用
收藏
页码:2192 / 2194
页数:3
相关论文
共 23 条
[1]   Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae isolates in Canada, 1997 to 2005 [J].
Adam, Heather J. ;
Schurek, Kristen N. ;
Nichol, Kimberly A. ;
Hoban, Chris J. ;
Baudry, Trish J. ;
Laing, Nancy M. ;
Hoban, Daryl J. ;
Zhanel, George G. .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (01) :198-207
[2]  
*CLIN LAB STAND I, 2004, PERF STAND ANT SUSC
[3]   Evaluation of bacterial kill when modelling the bronchopulmonary pharmacokinetic profile of moxifloxacin and levofloxacin against parC-containing isolates of Streptococcus pneumoniae [J].
DeRyke, C. Andrew ;
Du, Xiaoli ;
Nicolau, David P. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2006, 58 (03) :601-609
[4]   Antimicrobial resistance among Streptococcus pneumoniae in the United States:: Have we begun to turn the corner on resistance to certain antimicrobial classes? [J].
Doern, GV ;
Richter, SS ;
Miller, A ;
Miller, N ;
Rice, C ;
Heilmann, K ;
Beekmann, S .
CLINICAL INFECTIOUS DISEASES, 2005, 41 (02) :139-148
[5]   A review of Streptococcus pneumoniae infection treatment failures associated with fluoroquinolone resistance [J].
Fuller, JD ;
Low, DE .
CLINICAL INFECTIOUS DISEASES, 2005, 41 (01) :118-121
[6]   Genetic relatedness within and between serotypes of Streptococcus pneumoniae from the United Kingdom: Analysis of multilocus enzyme electrophoresis, pulsed-field gel electrophoresis, and antimicrobial resistance patterns [J].
Hall, LMC ;
Whiley, RA ;
Duke, B ;
George, RC ;
Efstratiou, A .
JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (04) :853-859
[7]   Increasing resistance of Streptococcus pneumoniae to fluoroquinolones:: results of a Hong Kong multicentre study in 2000 [J].
Ho, PL ;
Yung, RWH ;
Tsang, DNC ;
Que, TL ;
Ho, M ;
Seto, WH ;
Ng, TK ;
Yam, WC ;
Ng, WWS .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2001, 48 (05) :659-665
[8]   Fluoroquinolone resistance among Streptococcus pneumoniae in Hong Kong linked to the Spanish 23F clone [J].
Ho, PL ;
Yam, WC ;
Cheung, TKM ;
Ng, WWS ;
Que, TL ;
Tsang, DNC ;
Ng, TK ;
Seto, WH .
EMERGING INFECTIOUS DISEASES, 2001, 7 (05) :906-908
[9]   Risk factors for acquisition of levofloxacin-resistant Streptococcus pneumoniae:: A case-control study [J].
Ho, PL ;
Tse, WS ;
Tsang, KWT ;
Kwok, TK ;
Ng, TK ;
Cheng, VCC ;
Chan, RMT .
CLINICAL INFECTIOUS DISEASES, 2001, 32 (05) :701-707
[10]   Evidence of clonal dissemination of multidrug-resistant Streptococcus pneumoniae in Hong Kong [J].
Ip, M ;
Lyon, DJ ;
Yung, RWH ;
Chan, CL ;
Cheng, AFB .
JOURNAL OF CLINICAL MICROBIOLOGY, 1999, 37 (09) :2834-2839