I2-Promoted [3+2] Cyclization of 1,3-Diketones with Potassium Thiocyanate: a Route to Thiazol-2(3H)-One Derivatives

被引：16
作者：
An, Zhenyu [1 ]
Liu, Yafeng [2 ]
Zhao, Pengbo [1 ]
Yan, Rulong [1 ]
机构：
[1] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China
[2] North Minzu Univ, Chem Sci & Engn Coll, Yinchuan 750000, Ningxia, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2021年 / 363卷 / 13期
基金：
中国国家自然科学基金;
关键词：
1,3-Diketones; Potassium thiocyanate; Thiazol-2(311)-ones; Transition-metal-free; Cyclization; BIOLOGICAL-ACTIVITY; VINYL AZIDES; C-N; ACCESS; CONSTRUCTION; INHIBITORS; DISCOVERY; BENZOTHIAZOLONES; 2-AMINOTHIAZOLES; CYTOTOXICITY;
D O I：
10.1002/adsc.202100228
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
An I-2 -promoted strategy has been developed for the synthesis of thiazol-2(3H)-one derivatives from 1,3-diketones with potassium thiocyanate. This [3 + 2] cyclization reaction involves C-S and C-N bond formation and exhibits good functional group tolerance. A series of thiazol-2(3H)-one derivatives are obtained in moderate to good yields.
引用
收藏
页码：3240 / 3244
页数：5
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