Transgenic mouse expressing a full-length hepatitis C virus cDNA

被引：24

作者：

Matsuda, J

Suzuki, M

Nozaki, C

Shinya, N

Tashiro, K

Mizuno, K

Uchinuno, Y

Yamamura, K

机构：

[1] Kikuchi Res Ctr, Chemo Sero Therapeut Res Inst, Good Lab Practice GLP Ctr, Dept Pathol, Kumamoto 86912, Japan

[2] Kumamoto Univ, Inst Mol Embryol & Genet, Dept Dev Genet, Kumamoto 862, Japan

来源：

JAPANESE JOURNAL OF CANCER RESEARCH | 1998年 / 89卷 / 02期

关键词：

hepatitis C virus; transgenic mouse; human serum amyloid P component (hSAP) promoter;

D O I：

10.1111/j.1349-7006.1998.tb00543.x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hepatitis C virus (HCV), a major causative agent of post transfusion non-A, non-B hepatitis (NANBH), can only infect humans and chimpanzees, We produced nine transgenic mouse lines carrying a full-length HCV cDNA with the human serum amyloid P component (hSAP) promoter that can direct liver-specific expression, In one of these lines HCV mRNA and HCV core protein were detected in the liver of the transgenic mouse, although the levels of expression were very low. In addition, HCV-related antibody was detected in the serum.

引用

页码：150 / 158

页数：9

共 50 条

[31] Construction of an infectious full-length cDNA clone of Chrysanthemum virus B
Ohkawa, Atsushi
Ishikawa-Suehiro, Noriko
Okuda, Seiichi
Natsuaki, Tomohide
JOURNAL OF GENERAL PLANT PATHOLOGY, 2008, 74 (06) : 434 - 437
[32] Refolding of the full-length non-structural protein 3 of hepatitis C virus
Poliakov, A
Danielson, UH
PROTEIN EXPRESSION AND PURIFICATION, 2005, 41 (02) : 298 - 305
[33] Robust full-length hepatitis C virus infection effect to host transcription factors
Shao, Run-Xuan
Kato, Naoya
Moriyama, Masaru
Muroyama, Ryosuke
Otsuka, Motoyuki
Dharel, Narayanl
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2006, 21 : A27 - A27
[34] A method for near full-length amplification and sequencing for six hepatitis C virus genotypes
Rowena A. Bull
Auda A. Eltahla
Chaturaka Rodrigo
Sylvie M. Koekkoek
Melanie Walker
Mehdi R. Pirozyan
Brigid Betz-Stablein
Armin Toepfer
Melissa Laird
Steve Oh
Cheryl Heiner
Lisa Maher
Janke Schinkel
Andrew R. Lloyd
Fabio Luciani
BMC Genomics, 17
[35] A method for near full-length amplification and sequencing for six hepatitis C virus genotypes
Bull, Rowena A.
Eltahla, Auda A.
Rodrigo, Chaturaka
Koekkoek, Sylvie M.
Walker, Melanie
Pirozyan, Mehdi R.
Betz-Stablein, Brigid
Toepfer, Armin
Laird, Melissa
Oh, Steve
Heiner, Cheryl
Maher, Lisa
Schinkel, Janke
Lloyd, Andrew R.
Luciani, Fabio
BMC GENOMICS, 2016, 17
[36] Microarray analysis of liver cells containing a full-length hepatitis C virus replicon
Ciccaglione, A.
Marcantonio, C.
Bruni, R.
Tritarelli, E.
Costantino, A.
Tataseo, P.
Rapicetta, M.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2007, 29 : S406 - S406
[37] Persistent and transient replication of full-length hepatitis C virus genomes in cell culture
Pietschmann, T
Lohmann, V
Kaul, A
Krieger, N
Rinck, G
Rutter, G
Strand, D
Bartenschlager, R
JOURNAL OF VIROLOGY, 2002, 76 (08) : 4008 - 4021
[38] Full-length genome sequences of hepatitis C virus subtype 4f
Hmaied, Fatma
Legrand-Abravanel, Florence
Nicot, Florence
Garrigues, Natalie
Chapuy-Regaud, Sabine
Dubois, Martine
Njouom, Richard
Izopet, Jacques
Pasquier, Christophe
JOURNAL OF GENERAL VIROLOGY, 2007, 88 : 2985 - 2990
[39] Expression of a full-length hepatitis C virus cDNA up-regulates the expression of CC chemokines MCP-1 and RANTES
Soo, HM
Garzino-Demo, A
Hong, WJ
Tan, YH
Tan, YJ
Goh, PY
Lim, SG
Lim, SP
VIROLOGY, 2002, 303 (02) : 253 - 277
[40] CLONING OF THE FULL-LENGTH CDNA AND THE GENE OF MOUSE PEMPHIGUS-VULGARIS ANTIGEN
ISHIKAWA, H
LI, K
SILOS, S
TAMAI, K
MOTOKI, K
UITTO, J
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1995, 104 (04) : 638 - 638

← 1 2 3 4 5 →