Magna ease bioprosthetic aortic valve: mid-term haemodynamic outcomes in 1126 patients

被引:12
作者
Thorp, Stephen D. [1 ]
Khazaal, Jawad [2 ]
Yu, Grace [2 ]
Parker, Jessica L. [3 ]
Timek, Tomasz A. [4 ]
机构
[1] Michigan State Univ, Spectrum Hlth, Gen Surg Residency, Grand Rapids, MI USA
[2] Michigan State Univ, Coll Human Med, Grand Rapids, MI USA
[3] Spectrum Hlth, Off Res & Educ, Grand Rapids, MI 49503 USA
[4] Spectrum Hlth, Div Cardiothorac Surg, 100 Michigan NE, Grand Rapids, MI 49503 USA
关键词
Magna ease; Haemodynamic; Structural valve deterioration; LONG-TERM OUTCOMES; REPLACEMENT;
D O I
10.1093/icvts/ivab016
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVES: The Magna Ease aortic valve (Edwards Lifesciences, Irvine, CA) is a third-generation bioprosthetic valve developed as a modification of the well-studied Perimount and Magna valve designs. This study's objective is to evaluate a large, single-centre experience with Magna Ease aortic valve replacement (AVR) focusing on clinical outcomes and haemodynamic performance. METHODS: All patients undergoing AVR between 8/2010 and 10/2018 at our institution implanted with the Magna Ease valve were included except those undergoing ventricular assist device or congenital aortic surgery. Primary outcomes were overall survival and freedom from reoperation. Mean transprosthetic gradient (mTPG) and structural valve deterioration (SVD) served as secondary outcomes. RESULTS: Totally 1126 consecutive implantations of Magna Ease valves were included. Concomitant procedures were performed in 56.5% (n = 636). No severe patient-prosthesis mismatch (PPM) was present at implantation. Overall survival at 30 days, 1 year, 5 years and 9 years was 97.2%, 95.0%, 86.1% and 78.2%, respectively, with improved survival for isolated AVR. Total of 2.4% (n = 27) of patients required reoperation with 0.3% (n = 4) for SVD. Echocardiographic follow-up data revealed low mTPG throughout the study period. SVD occurred in 28.7% of patients at a mean of 3.9 years post implantation. CONCLUSIONS: Magna Ease AVR maintained low mean transprosthetic gradients throughout mid-term evaluation and was associated with excellent overall survival and freedom from reoperation at nine years post implantation.
引用
收藏
页码:839 / 845
页数:7
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