WHO Pathology br Highlights of the 2020 Sarcoma Update

被引:10
|
作者
Schaefer, Inga-Marie [1 ]
Gronchi, Alessandro [2 ]
机构
[1] Harvard Med Sch, Brigham & Womens Hosp, Dept Pathol, 75 Francis St, Boston, MA 02115 USA
[2] Fdn IRCCS Ist Nazl Tumori, Dept Surg, Via Giacomo Venezian 1, I-20133 Milan, Italy
基金
美国国家卫生研究院;
关键词
WHO classification; Sarcoma; Liposarcoma; Leiomyosarcoma; Round cell sarcoma; Rearrangement; Risk stratification; Marker; CD34-POSITIVE FIBROBLASTIC TUMOR; CELL LIPOMATOUS TUMOR; INFLAMMATORY-LEIOMYOSARCOMA; NEAR-HAPLOIDIZATION; MOLECULAR ANALYSIS; GENETIC-ANALYSIS; ANGIOFIBROMA; SPECTRUM; LIPOSARCOMAS; EXPRESSION;
D O I
10.1016/j.soc.2022.03.001
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The 2020 WHO Classification of Soft Tissue and Bone Tumors includes several novel and emerging entities and features a number of revisions to existing classification and risk stratification schemes to incorporate recent advances in the diagnostic workup of these tumors. This update integrates a morphology-based approach combined with evaluation for characteristics of cytogenetic/molecular genetic alterations and associated immunohistochemical markers to improve diagnostic precision, reproducibility, and prognostication for state-of-the-art clinical management.
引用
收藏
页码:321 / 340
页数:20
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