Megakaryocytes in the hematopoietic stem cell niche

被引:11
作者
Day, Ryan B. [1 ]
Link, Daniel C. [1 ]
机构
[1] Washington Univ, Dept Med, St Louis, MO 63130 USA
关键词
BONE-MARROW NICHE; MAINTENANCE; QUIESCENCE;
D O I
10.1038/nm.3745
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Mesenchymal stromal cells are key components of hematopoietic stem cell (HSC) niches in the bone marrow. Two studies now show that hematopoietic-derived megakaryocytes also contribute to the HSC niche, regulating HSC quiescence and function.
引用
收藏
页码:1233 / 1234
页数:2
相关论文
共 11 条
[11]   Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells [J].
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