The transmission of phocine herpesvirus-1 in rehabilitating and free-ranging Pacific harbor seals (Phoca vitulina) in California

被引:23
作者
Goldstein, T
Mazet, JAK
Gulland, FMD
Rowles, T
Harvey, JT
Allen, SG
King, DP
Aldridge, BM
Stott, JL
机构
[1] Univ Calif Davis, Wildlife Hlth Ctr, Sch Vet Med, Davis, CA 95616 USA
[2] Marine Mammal Ctr, Sausalito, CA 95695 USA
[3] Univ Calif Davis, Lab Marine Mammal Immunol, Dept Pathol Microbiol & Immunol, Sch Vet Med, Davis, CA 95616 USA
[4] Natl Marine Fisheries Serv, Off Protected Resources, Silver Spring, MD 20910 USA
[5] Moss Landing Marine Labs, Moss Landing, CA 95039 USA
[6] Point Reyes Natl Seashores, Natl Pk Serv, Point Reyes Stn, CA 94956 USA
关键词
harbor seal; Phoca vitulina; phocine herpesvirus; viral transmission; PCR; ELISA;
D O I
10.1016/j.vetmic.2004.06.017
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Phocine herpesvirus-1 (PhHV-1) causes regular outbreaks of disease in neonatal harbor seals (Phoca vitulina) at rehabilitation centers in Europe and in the U.S. To investigate transmission of this virus samples were collected from harbor seal pups during exposure studies at a Californian rehabilitation center from 1999 to 2002 and from free-ranging harbor seals off central California during the same period. The exposure studies provided evidence that PhHV-1 can be transmitted horizontally between animals most likely through direct contact with oro-nasal secretions. However vertical transmission may also occur, as adult female harbor seals were found to be shedding the virus in vaginal and nasal secretions, and premature newborn pups had evidence of early infection. Results also indicated that PhHV-1 infections were common in both free-ranging (40%, 49/121) and rehabilitating (54%, 46/85) young harbor seals, during the spring and early summer. This timing, which correlated with pupping and weaning, suggested that the majority of animals were infected and infective with PhHV-1 between pupping and breeding. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:131 / 141
页数:11
相关论文
共 30 条
[1]  
Bigg M. A., 1969, Bulletin Fisheries Research Board of Canada, VNo. 172, P1
[2]   CLINES IN PUPPING SEASON OF HARBOUR SEAL PHOCA VITULINA [J].
BIGG, MA .
JOURNAL OF THE FISHERIES RESEARCH BOARD OF CANADA, 1969, 26 (02) :449-&
[3]  
Bossart GD, 2001, CRC HANDBOOK OF MARINE MAMMAL MEDICINE, SECOND EDITION, P383, DOI 10.1201/9781420041637.sec4
[4]  
BOULVA J., 1979, FISHERIES RES BOARD, V200, P1
[5]  
BUDDINGH GJ, 1953, PEDIATRICS, V11, P595
[6]  
Carmichael LE, 1990, INFECT DIS DOG CAT, P252
[7]  
DOUGLAS R G JR, 1970, Journal of Immunology, V104, P289
[8]   The logic of inductive inference [J].
Fisher, RA .
JOURNAL OF THE ROYAL STATISTICAL SOCIETY, 1935, 98 :39-82
[9]  
FLEISS JL, 1981, STATISTICAL METHODS, P58
[10]   Antibodies to phocine herpesvirus-1 are common in North American harbor seals (Phoca vitulina) [J].
Goldstein, T ;
Gulland, FMD ;
Aldridge, BM ;
Harvey, JT ;
Rowles, T ;
Lambourn, DM ;
Jeffries, SJ ;
Measures, L ;
Yochem, PK ;
Stewart, BS ;
Small, RJ ;
King, DP ;
Stott, JL ;
Mazet, JAK .
JOURNAL OF WILDLIFE DISEASES, 2003, 39 (03) :487-494