Multilineage potential of adult human mesenchymal stromal cells derived from bone marrow of patients with polycytaemia vera

被引：1

作者：

Holovska, Vanda ^{[1
,2
]}

Rosocha, Jan ^{[1
,2
]}

Lehocka, Lenka ^{[1
,2
]}

Kafkova, Adriana ^{[2
,3
]}

Cizkova, Dasa ^{[4
]}

Rosocha, Ladislav ^{[5
,6
]}

机构：

[1] Safarik Univ, Fac Med, Tissue Bank, SK-04066 Kosice, Slovakia

[2] L Pasteur Fac Hosp Kosice, SK-04066 Kosice, Slovakia

[3] Safarik Univ, Fac Med, Dept Haematol & Oncohematol, SK-04066 Kosice, Slovakia

[4] Slovak Acad Sci, Inst Neurobiol, SK-04001 Kosice, Slovakia

[5] Safarik Univ, Fac Med, Dept Gynaecol & Obstet 2, SK-04190 Kosice, Slovakia

[6] L Pasteur Fac Hosp Kosice, SK-04190 Kosice, Slovakia

来源：

BIOLOGIA | 2010年 / 65卷 / 02期

关键词：

mesenchymal stromal cells; polycytaemia vera; multilineage differentiation; CHRONIC MYELOID-LEUKEMIA; UMBILICAL-CORD BLOOD; EX-VIVO EXPANSION; STEM-CELLS; CULTURE; DIFFERENTIATION; PROGENITORS; MATRIX;

D O I：

10.2478/s11756-010-0012-z

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Human mesenchymal stromal cells were isolated from the bone marrow of patients with polycyteamia vera (the myeloproliferative disorder) with the aim to characterize the properties of the mesenchymal stromal cells originating from the pathologically affected bone marrow. Their in vitro growth and potential to differentiate were determined. Isolated mesenchymal stromal cells were able to differentiate into three mesenchymal lineages under appropriate cultivation conditions.

引用

页码：372 / 378

页数：7

共 40 条

[11]

Fernandez-Luna JL, 1998, HAEMATOLOGICA, V83, P150

[12] Hepatic stem cells [J].

Forbes, S ;

Vig, P ;

Poulsom, R ;

Thomas, H ;

Alison, M .

JOURNAL OF PATHOLOGY, 2002, 197 (04) :510-518

[13]

Frassoni FLM, 2002, BONE MARROW TRANSPL, V29, P75

[14] Mammalian neural stem cells [J].

Gage, FH .

SCIENCE, 2000, 287 (5457) :1433-1438

[15]

HOFFBRAND VA, 2000, COLOUR ATLAS CLIN HE

[16] Cardiac stem cells [J].

Hughes, S .

JOURNAL OF PATHOLOGY, 2002, 197 (04) :468-478

[17] In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells [J].

Johnstone, B ;

Hering, TM ;

Caplan, AI ;

Goldberg, VM ;

Yoo, JU .

EXPERIMENTAL CELL RESEARCH, 1998, 238 (01) :265-272

[18] Bone marrow derived mesenchymal stem cells from chronic myeloid leukemia t(9;22) patients are devoid of Philadelphia chromosome and support cord blood stem cell expansion [J].

Jootar, Saengsuree ;

Pornprasertsud, Nida ;

Petvises, Sawang ;

Rerkamnuaychoke, Busaba ;

Disthabanchong, Sinee ;

Pakakasama, Samart ;

Ungkanont, Artit ;

Hongeng, Suradej .

LEUKEMIA RESEARCH, 2006, 30 (12) :1493-1498

[19] Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy [J].

Koç, ON ;

Gerson, SL ;

Cooper, BW ;

Dyhouse, SM ;

Haynesworth, SE ;

Caplan, AI ;

Lazarus, HM .

JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (02) :307-316

[20] Defining optimum conditions for the ex vivo expansion of human umbilical cord blood cells.: Influences of progenitor enrichment, interference with feeder layers, early-acting cytokines and agitation of culture vessels [J].

Köhler, T ;

Plettig, R ;

Wetzstein, W ;

Schaffer, B ;

Ordemann, R ;

Nagels, HO ;

Ehninger, G ;

Bornhäuser, M .

STEM CELLS, 1999, 17 (01) :19-24

← 1 2 3 4 →