Renal aquaporin water channels: from molecules to human disease

被引：47
作者：
Schrier, RW
Cadnapaphornchai, MA
机构：
[1] Univ Colorado, Sch Med, Dept Med, Denver, CO 80262 USA
[2] Univ Colorado, Sch Med, Dept Pediat, Denver, CO 80262 USA
来源：
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY | 2003年 / 81卷 / 02期
关键词：
D O I：
10.1016/S0079-6107(02)00049-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Following the discovery of the aquaporin-1 water channel in 1991, molecular techniques have been developed to examine the roles of renal aquaporins-1, -2, -3, and -4 in disorders of water balance. This article reviews current knowledge regarding aquaporin function and dysfunction in water-losling and water-retaining states. (C) 2002 Elsevier Science Ltd. All rights reserved.
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页码：117 / 131
页数：15
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