Rhodium(II)-carbenoid C-H insertion reactions in the synthesis of β-oxospirane systems

被引：17

作者：

Aburel, PS ^{[1
]}

Undheim, K ^{[1
]}

机构：

[1] Univ Oslo, Dept Chem, N-0315 Oslo, Norway

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2000年 / 12期

关键词：

D O I：

10.1039/b001988g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple one-pot procedure is described for the preparation of spiro[4.4]nonane-2,7-dione derivatives from open chain bis(alpha-diazoketones) by two consecutive intramolecular Rh(II)-catalyzed carbenoid insertion reactions. With 1-diazo-4-(3-oxocycloalkyl)butan-2-ones as substrates, the methodology provides 2,7-dioxospiranes with a cyclopentane ring spiroannulated onto a five-, six- or seven-membered cycloalkane.

引用

页码：1891 / 1896

页数：6

共 26 条

[1] Synthesis of spirosystems by rhodium(II)-carbenoid C-H insertion reactions. [J].