Physical Stability, Rheological Analysis and Antioxidant Study of Cetyl Dimethicone Copolyol Based Cosmetic Water-In-Oil Emulsions

被引:0
作者
Waqas, Muhammad K. [1 ]
Akhtar, Naveed [1 ]
Jamil, Qazi A. [1 ]
Ijaz, Shakeel [1 ]
Khan, Haji M. S. [1 ]
Murtaza, Ghulam [2 ]
机构
[1] Islamia Univ Bahawalpur, Fac Pharm & Alternat Med, Dept Pharm, Bahawalpur, Pakistan
[2] COMSATS Inst Informat Technol, Dept Pharm, Abbottabad 22060, Pakistan
来源
LATIN AMERICAN JOURNAL OF PHARMACY | 2014年 / 33卷 / 10期
关键词
Cosmetic emulsions; pH; Rheology; Stability; Viscosity; EXTRACT; GENISTEIN; CREAM; SEEDS; FORMULATION;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The aim of current study was to explore alterations in physical stability parameters ( viscosity, centrifugation, conductivity, pH, liquefaction, creaming, and color) and rheological analysis of water in oil (W/O) non-ionic emulsifier, cetyl dimethicone copolyol, of based cosmetic emulsions following addition of botanical extract (4% soybean seeds extract). The evaluation of physical stability was done by keeping the emulsions to storage conditions at 8 +/- 0.5 degrees C, 25 +/- 0.5 degrees C, 40 +/- 0.5 degrees C, and at 40 +/- 0.5 degrees C with 70% relative humidity (RH) for duration of three months. Organoleptic and physical properties ( color, creaming, centrifugation, liquefaction and pH) were examined at various time intervals for a period of three months. Cosmetic emulsion with botanical extract exhibited pseudoplastic behavior with declining viscosity. The results of current study demonstrate that cosmetic emulsion loaded with 4% soybean seeds extract showed excellent stability over three months study duration which represents that W/O non-ionic emulsifier cetyl dimethicone copolyol based cosmetic emulsions can be used as carrier for 4% soybean seeds extract to improve the required outcomes.
引用
收藏
页码:1655 / 1661
页数:7
相关论文
共 22 条
  • [1] Akhtar N, 2010, TROP J PHARM RES, V9, P329
  • [2] [Anonymous], 2006, RHEOLOGY ESSENTIALS
  • [3] Influence of the particle type on the rheological behavior of Pickering emulsions
    Chen, J.
    Vogel, R.
    Werner, S.
    Heinrich, G.
    Clausse, D.
    Dutschk, V.
    [J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2011, 382 (1-3) : 238 - 245
  • [4] UVB-protective effects of isoflavone extracts from soybean cake in human keratinocytes
    Chiang, Han-Sun
    Wu, Wen-Bin
    Fang, Jia-You
    Chen, Bing-Huei
    Kao, Tsai-Hua
    Chen, Ying-Ting
    Huang, Chieh-Chen
    Hung, Chi-Feng
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2007, 8 (07): : 651 - 661
  • [5] Rheology of Decamethylceclopentasiloxane (cyclomethicone) W/O Emulsion System
    Choi, Min Hyung
    Jeong, Sora
    Nam, Sang In
    Shim, Sang Eun
    Chang, Yoon Ho
    [J]. MACROMOLECULAR RESEARCH, 2009, 17 (12) : 943 - 949
  • [6] Rheology of emulsions
    Derkach, Svetlana R.
    [J]. ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2009, 151 (1-2) : 1 - 23
  • [7] Genistein
    Dixon, RA
    Ferreira, D
    [J]. PHYTOCHEMISTRY, 2002, 60 (03) : 205 - 211
  • [8] Antibacterial activity of the soy isoflavone genistein
    Hong, Hyunki
    Landauer, Michael R.
    Foriska, Mark A.
    Ledney, G. David
    [J]. JOURNAL OF BASIC MICROBIOLOGY, 2006, 46 (04) : 329 - 335
  • [9] A rheological method to evaluate the physical stability of highly viscous pharmaceutical oil-in-water emulsions
    Masmoudi, Houda
    Piccerelle, Philippe
    Le Dreau, Yveline
    Kister, Jacky
    [J]. PHARMACEUTICAL RESEARCH, 2006, 23 (08) : 1937 - 1947
  • [10] Caffeic Acid Phenethyl Ester and Therapeutic Potentials
    Murtaza, Ghulam
    Karim, Sabiha
    Akram, Muhammad Rouf
    Khan, Shujaat Ali
    Azhar, Saira
    Mumtaz, Amara
    Bin Asad, Muhammad Hassham Hassan
    [J]. BIOMED RESEARCH INTERNATIONAL, 2014, 2014