Toddlers with Elevated Autism Symptoms Show Slowed Habituation to Faces

被引：73

作者：

Webb, Sara Jane ^{[1
,2
]}

Jones, Emily J. H. ^{[1
]}

Merkle, Kristen ^{[1
]}

Namkung, Jessica ^{[1
]}

Toth, Karen ^{[3
]}

Greenson, Jessica ^{[1
,2
]}

Murias, Michael ^{[1
,2
]}

Dawson, Geraldine ^{[1
,4
,5
,6
]}

机构：

[1] Univ Washington, Autism Ctr, Seattle, WA 98195 USA

[2] Univ Washington, Ctr Human Dev & Disabil, Seattle, WA 98195 USA

[3] Seattle Childrens, Seattle, WA USA

[4] Univ Washington, Dept Psychol, Seattle, WA 98195 USA

[5] Univ N Carolina, Dept Psychiat, Chapel Hill, NC USA

[6] Autism Speaks, New York, NY USA

来源：

CHILD NEUROPSYCHOLOGY | 2010年 / 16卷 / 03期

关键词：

Habituation; Autism; ASD; Face processing; Toddlers; Broader phenotype; TERM RECOGNITION MEMORY; SPECTRUM DISORDER; YOUNG-CHILDREN; DEVELOPMENTAL PROSOPAGNOSIA; INDIVIDUAL-DIFFERENCES; METHODOLOGICAL ISSUES; 2-YEAR-OLD TODDLERS; INFANT HABITUATION; PERCEPTION; SIBLINGS;

D O I：

10.1080/09297041003601454

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We explored social information processing and its relation to social and communicative symptoms in toddlers with Autism Spectrum Disorder (ASD) and their siblings. Toddlers with more severe symptoms of autism showed slower habituation to faces than comparison groups; slower face learning correlated with poorer social skills and lower verbal ability. Unaffected toddlers who were siblings of children with ASD also showed slower habituation to faces compared with toddlers without siblings with ASD. We conclude that slower rates of face learning may be an endophenotype of ASD and is associated with more severe symptoms among affected individuals.

引用

页码：255 / 278

页数：24

共 103 条

[31]

FAGAN JF, 1974, CHILD DEV, V45, P351

[32] RECOGNITION MEMORY AND INTELLIGENCE [J].

FAGAN, JF .

INTELLIGENCE, 1984, 8 (01) :31-36

[33] The genetics of autistic disorders and its clinical relevance: a review of the literature [J].

Freitag, C. M. .

MOLECULAR PSYCHIATRY, 2007, 12 (01) :2-22

[34] Brief report: Early social communication behaviors in the younger siblings of children with autism [J].

Goldberg, WA ;

Jarvis, KL ;

Osann, K ;

Laulhere, TM ;

Straub, C ;

Thomas, E ;

Filipek, P ;

Spence, MA .

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 2005, 35 (05) :657-664

[35] The endophenotype concept in psychiatry: Etymology and strategic intentions [J].

Gottesman, II ;

Gould, TD .

AMERICAN JOURNAL OF PSYCHIATRY, 2003, 160 (04) :636-645

[36] Social interest and the development of cortical face specialization: What autism teaches us about face processing [J].

Grelotti, DJ ;

Gauthier, I ;

Schultz, RT .

DEVELOPMENTAL PSYCHOBIOLOGY, 2002, 40 (03) :213-225

[37] Measuring infant memory: Does the ruler matter? [J].

Gross, J ;

Hayne, H ;

Herbert, J ;

Sowerby, P .

DEVELOPMENTAL PSYCHOBIOLOGY, 2002, 40 (02) :183-192

[38] Recent advances in the genetics of autism [J].

Gupta, Abha R. ;

State, Matthew W. .

BIOLOGICAL PSYCHIATRY, 2007, 61 (04) :429-437

[39] Memory for faces in children with autism [J].

Hauck, M ;

Fein, D ;

Maltby, N ;

Waterhouse, L ;

Feinstein, C .

CHILD NEUROPSYCHOLOGY, 1998, 4 (03) :187-198

[40] METHODOLOGICAL ISSUES FOR EXPERIMENTS ON AUTISTIC INDIVIDUALS PERCEPTION AND UNDERSTANDING OF EMOTION [J].

HOBSON, RP .

JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES, 1991, 32 (07) :1135-1158

← 1 2 3 4 5 6 7 8 9 10 →