Reirradiation for locally recurrent breast cancer

被引:14
作者
Marta, Gustavo Nader [1 ,2 ]
Hijal, Tarek [3 ]
de Andrade Carvalho, Heloisa [1 ,4 ]
机构
[1] Hosp Sirio Libanes, Dept Radiat Oncol, Rua Dona Adma Jafet 91, BR-01308050 Sao Paulo, SP, Brazil
[2] Univ Sao Paulo, Dept Radiol & Oncol, Inst Canc Estado Sao Paulo ICESP FMUSP, Sao Paulo, Brazil
[3] McGill Univ, Hlth Ctr, Div Radiat Oncol, Montreal, PQ, Canada
[4] Univ Sao Paulo, Dept Radiol & Oncol, Inst Radiol, Hosp Clin,Fac Med, Sao Paulo, Brazil
关键词
Breast cancer; Radiation therapy; Recurrence; Treatment; Reirradiation; 2ND CONSERVATIVE TREATMENT; RADIATION-THERAPY; TUMOR RECURRENCE; PROGNOSTIC-FACTORS; CHEST-WALL; HYPERTHERMIA; RADIOTHERAPY; SURGERY; BRACHYTHERAPY; IRRADIATION;
D O I
10.1016/j.breast.2017.03.008
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The aim of this study is to review the current status of reirradiation therapy (Re-RT) for locally recurrent breast cancer. The overall outcome of breast/chest wall Re-RT is difficult to assess because of the wide range of different treatments that a patient may have undergone and the patient's individual features. The local control and complete response rates were reported to be 43-96% and 41-71%, respectively. The combination of Re-RT and hyperthermia seems to be related to improved outcomes. Toxicity rates vary between studies, and Re-RT is generally well tolerated. Re-RT may be considered an option for patients with breast cancer relapse after prior irradiation. Further studies are needed to determine the best irradiation volume and treatment modality for patients with locally recurrent disease. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码:159 / 165
页数:7
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