Pregnancy in Patients with Cushing's Syndrome

被引：21

作者：

Machado, Marcio Carlos ^{[1
,2
,3
]}

Barisson Vilares Fragoso, Maria Candida ^{[1
]}

Bronstein, Marcello Delano ^{[1
]}

机构：

[1] Univ Sao Paulo, Med Sch, Neuroendocrine Unit, Div Endocrinol & Metab,Hosp Clin, Ave Eneas de Carvalho Aguiar 155,8 Andar,Bloco 03, BR-05403000 Sao Carlos, SP, Brazil

[2] AC Camargo Canc Ctr, Endocrinol Serv, Rua Prof Antonio Prudente 211, BR-01509010 Sao Paulo, SP, Brazil

[3] Univ Sao Paulo, Med Sch, Lab Endocrinol Cellular & Mol LIM25, Av Dr Arnaldo 455,4 Andar, BR-01246903 Sao Paulo, SP, Brazil

来源：

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 2018年 / 47卷 / 02期

关键词：

Cushing's syndrome; Pregnancy; Hypercortisolism; CORTICOTROPIN-RELEASING HORMONE; CRH-BINDING-PROTEIN; OF-THE-LITERATURE; LAPAROSCOPIC ADRENALECTOMY; PITUITARY-TUMORS; DISEASE; KETOCONAZOLE; METYRAPONE; CORTISOL; PATTERNS;

D O I：

10.1016/j.ecl.2018.02.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Progress in diagnosis and treatment of endocrine diseases has made pregnancy possible for women with endocrinopathies, including Cushing's syndrome (CS). The risk of maternal-fetal complications in patients who are not biochemically controlled, however, is substantial. Therefore, the surgical and/or medical control of hypercortisolism is mandatory before conceiving. A diagnosis of de novo CS during gestation is difficult because of changes in the hypothalamic-pituitary-adrenal axis during pregnancy, which may lead to some clinical features suggestive of CS along with abnormal laboratory test results. This article presents the diagnosis and management of CS during pregnancy.

引用

页码：441 / +

页数：10

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