Myocarditis Following the Second Dose of COVID-19 Vaccination in a Japanese Adolescent

被引：3

作者：

Yamamoto, Shohei ^{[1
]}

Arita, Yoh ^{[1
]}

Ogasawara, Nobuyuki ^{[1
]}

机构：

[1] Japan Community Healthcare Org Osaka Hosp, Dept Cardiol, Osaka, Japan

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2022年 / 14卷 / 03期

关键词：

adolescent; myocarditis; vaccination; bnt162b2; mrna; covid-19;

D O I：

10.7759/cureus.23474

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

As COVID-19 vaccines continue to be deployed worldwide, countries are now planning to vaccinate their pediatric populations as well. However, several vaccine-related adverse events, including myocarditis, have been reported. Although the incidence of myocarditis after BNT I 62b2 vaccination is low, it is higher, particularly after receiving the second dose, among young male recipients. A 13-year-old male adolescent presented with chest pain after the second dose of the BNT162b2 vaccination. Electrocardiography, echocardiography, cardiac magnetic resonance imaging, and blood examinations were consistent with myocarditis. He was treated conservatively because his symptoms were relatively mild. In Japan, it is expected that the chances of diagnosing vaccine-related myocarditis will increase as more children are getting vaccinated. Our case report raises concerns to physicians that the COVID-19 vaccination may cause rare cases of myocarditis, which must always be considered as a differential diagnosis.

引用

页数：5

共 10 条

[1]

[Anonymous], 2022, COVID 19 VACCINE SAF

[2] Abnormal Extracardiac Development in Fetuses With Congenital Heart Disease [J].

Dovjak, Gregor O. ;

Zalewski, Tim ;

Seidl-Mlczoch, Elisabeth ;

Ulm, Patricia A. ;

Berger-Kulemann, Vanessa ;

Weber, Michael ;

Prayer, Daniela ;

Kasprian, Gregor J. ;

Ulm, Barbara .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2021, 78 (23) :2312-2322

[3] Safety, Immunogenicity, and Efficacy of the BNT162b2 Covid-19 Vaccine in Adolescents [J].

Frenck, Robert W., Jr. ;

Klein, Nicola P. ;

Kitchin, Nicholas ;

Gurtman, Alejandra ;

Absalon, Judith ;

Lockhart, Stephen ;

Perez, John L. ;

Walter, Emmanuel B. ;

Senders, Shelly ;

Bailey, Ruth ;

Swanson, Kena A. ;

Ma, Hua ;

Xu, Xia ;

Koury, Kenneth ;

Kalina, Warren V. ;

Cooper, David ;

Jennings, Timothy ;

Brandon, Donald M. ;

Thomas, Stephen J. ;

Tureci, Ozlem ;

Tresnan, Dina B. ;

Mather, Susan ;

Dormitzer, Philip R. ;

Sahin, Ugur ;

Jansen, Kathrin U. ;

Gruber, William C. .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (03) :239-250

[4] Myocarditis after BNT162b2 mRNA Vaccine against Covid-19 in Israel [J].

Mevorach, D. ;

Anis, E. ;

Cedar, N. ;

Bromberg, M. ;

Haas, E. J. ;

Nadir, E. ;

Olsha-Castell, S. ;

Arad, D. ;

Hasin, T. ;

Levi, N. ;

Asleh, R. ;

Amir, O. ;

Meir, K. ;

Cohen, D. ;

Dichtiar, R. ;

Novick, D. ;

Hershkovitz, Y. ;

Dagan, R. ;

Leitersdorf, I ;

Ben-Ami, R. ;

Miskin, I ;

Saliba, W. ;

Muhsen, K. ;

Levi, Y. ;

Green, M. S. ;

Keinan-Boker, L. ;

Alroy-Preis, S. .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (23) :2140-2149

[5] Myocarditis Following a COVID-19 Messenger RNA Vaccination: A Japanese Case Series [J].

Murakami, Yoshiki ;

Shinohara, Masaya ;

Oka, Yosuke ;

Wada, Ryo ;

Noike, Ryota ;

Ohara, Hiroshi ;

Fujino, Tadashi ;

Ikeda, Takanori .

INTERNAL MEDICINE, 2022, 61 (04) :501-505

[6]

Nagasaka Takashi, 2022, J Cardiol Cases, V25, P285, DOI 10.1016/j.jccase.2021.11.006

[7] Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021 [J].

Oster, Matthew E. ;

Shay, David K. ;

Su, John R. ;

Gee, Julianne ;

Creech, C. Buddy ;

Broder, Karen R. ;

Edwards, Kathryn ;

Soslow, Jonathan H. ;

Dendy, Jeffrey M. ;

Schlaudecker, Elizabeth ;

Lang, Sean M. ;

Barnett, Elizabeth D. ;

Ruberg, Frederick L. ;

Smith, Michael J. ;

Campbell, M. Jay ;

Lopes, Renato D. ;

Sperling, Laurence S. ;

Baumblatt, Jane A. ;

Thompson, Deborah L. ;

Marquez, Paige L. ;

Strid, Penelope ;

Woo, Jared ;

Pugsley, River ;

Reagan-Steiner, Sarah ;

DeStefano, Frank ;

Shimabukuro, Tom T. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2022, 327 (04) :331-340

[8] Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection [J].

Patone, Martina ;

Mei, Xue W. ;

Handunnetthi, Lahiru ;

Dixon, Sharon ;

Zaccardi, Francesco ;

Shankar-Hari, Manu ;

Watkinson, Peter ;

Khunti, Kamlesh ;

Harnden, Anthony ;

Coupland, Carol A. C. ;

Channon, Keith M. ;

Mills, Nicholas L. ;

Sheikh, Aziz ;

Hippisley-Cox, Julia .

NATURE MEDICINE, 2022, 28 (02) :410-+

[9] Myocarditis and pericarditis: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data [J].

Tejtel, S. Kristen Sexson ;

Munoz, Flor M. ;

Al-Ammouri, Iyad ;

Savorgnan, Fabio ;

Guggilla, Rama K. ;

Khuri-Bulos, Najwa ;

Phillips, Lee ;

Engler, Renata J. M. .

VACCINE, 2022, 40 (10) :1499-1511

[10] Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age [J].

Walter, E. B. ;

Talaat, K. R. ;

Sabharwal, C. ;

Gurtman, A. ;

Lockhart, S. ;

Paulsen, G. C. ;

Barnett, E. D. ;

Munoz, F. M. ;

Maldonado, Y. ;

Pahud, B. A. ;

Domachowske, J. B. ;

Simoes, E. A. F. ;

Sarwar, U. N. ;

Kitchin, N. ;

Cunliffe, L. ;

Rojo, P. ;

Kuchar, E. ;

Ramet, M. ;

Munjal, I ;

Perez, J. L. ;

Frenck, R. W., Jr. ;

Lagkadinou, E. ;

Swanson, K. A. ;

Ma, H. ;

Xu, X. ;

Koury, K. ;

Mather, S. ;

Belanger, T. J. ;

Cooper, D. ;

Tureci, O. ;

Dormitzer, P. R. ;

Jansen, K. U. ;

Gruber, W. C. .

NEW ENGLAND JOURNAL OF MEDICINE, 2022, 386 (01) :35-46

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