Neuroleptic sensitivity to clozapine in dementia with Lewy bodies

被引:45
作者
Burke, WJ
Pfeiffer, RF
McComb, RD
机构
[1] Univ Nebraska, Med Ctr, Dept Psychiat, Omaha, NE 68182 USA
[2] Univ Nebraska, Med Ctr, Dept Neurol, Omaha, NE 68182 USA
[3] Univ Nebraska, Med Ctr, Dept Pathol Microbiol, Omaha, NE 68182 USA
关键词
D O I
10.1176/jnp.10.2.227
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Dementia with Lewy bodies (DLB) may be one of the most common causes of dementia. It should be of particular interest to psychiatrists because hallucinations are common presenting symptoms and because patients with DLB may be particularly sensitive to neuroleptics with ? respect to developing extrapyramidal symptoms. The authors describe 2 patients with DLB who were intolerant of clozapine, showing not extrapyramidal side effects, but an increase in! confusion and behavioral symptoms.
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页码:227 / 229
页数:3
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