Computational fluid dynamics simulation of a novel bioreactor for sophorolipid production

被引：2

作者：

Jia, Xiaoqiang ^{[1
,2
,3
]}

Qi, Lin ^{[1
]}

Zhang, Yaguang ^{[1
]}

Yang, Xue ^{[1
]}

Wang, Hongna ^{[1
]}

Zhao, Fanglong ^{[1
]}

Lu, Wenyu ^{[1
,2
,3
]}

机构：

[1] Tianjin Univ, Sch Chem Engn & Technol, Dept Biochem Engn, Tianjin 300072, Peoples R China

[2] Tianjin Univ, Key Lab Syst Bioengn, Minist Educ, Tianjin 300072, Peoples R China

[3] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Synthet Biol Platform, Tianjin 300072, Peoples R China

来源：

CHINESE JOURNAL OF CHEMICAL ENGINEERING | 2017年 / 25卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Bioreactors; Gas hold-up; Computational fluid dynamics (CFD); Hydrodynamics; Sophorolipid production; BIOSURFACTANTS; FERMENTATION; BOMBICOLA;

D O I：

10.1016/j.cjche.2016.09.014

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

This paper describes three-dimensional computational fluid dynamics (CFD) simulations of gas-liquid flow in a novel laboratory-scale bioreactor contained dual ventilation-pipe and double sieve-plate bioreactor (DVDSB) used for sophorolipid (SL) production. To evaluate the role of hydrodynamics in reactor design, the comparisons between conventional fed-batch fermenter and DVDSB on the hydrodynamic behavior are predicted by the CFD methods. Important hydrodynamic parameters of the gas-liquid two-phase system such as the liquid phase velocity field, turbulent kinetic energy and volume-averaged overall and time-averaged local gas holdups were simulated and analyzed in detail. The numerical results were also validated by experimental measurements of overall gas holdups. The yield of sophorolipids was significantly improved to 484 g.L-1 with a 320 h fermentation period in the new reactor. (C) 2016 The Chemical Industry and Engineering Society of China, and Chemical Industry Press. All rights reserved.

引用

页码：732 / 740

页数：9

共 28 条

[1] BIOSURFACTANTS PRODUCTION AND POSSIBLE USES IN MICROBIAL ENHANCED OIL-RECOVERY AND OIL POLLUTION REMEDIATION - A REVIEW
BANAT, IM
[J]. BIORESOURCE TECHNOLOGY, 1995, 51 (01) : 1 - 12
[2] Effects of surfactant addition on the biomineralization and microbial toxicity of phenanthrene
Bramwell, DAP
Laha, S
[J]. BIODEGRADATION, 2000, 11 (04) : 263 - 277
[3] Daverey A., 2009, INT J ENV SCI ENG, V13, P481
[4] Daverey A, 2015, DESALIN WATER TREAT, V57, P1
[5] Production of sophorolipids by the yeast Candida bombicola using simple and low cost fermentative media
Daverey, Achlesh
Pakshirajan, Kannan
[J]. FOOD RESEARCH INTERNATIONAL, 2009, 42 (04) : 499 - 504
[6] Sophorose lipid fermentation with differentiated substrate supply for growth and production phases
Davila, AM
Marchal, R
Vandecasteele, JP
[J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1997, 47 (05) : 496 - 501
[7] CFD optimization of continuous stirred-tank (CSTR) reactor for biohydrogen production
Ding, Jie
Wang, Xu
Zhou, Xue-Fei
Ren, Nan-Qi
Guo, Wan-Qian
[J]. BIORESOURCE TECHNOLOGY, 2010, 101 (18) : 7005 - 7013
[8] Sophorolipids Production by Candida bombicola ATCC 22214 and its Potential Application in Microbial Enhanced Oil Recovery
Elshafie, Abdulkadir E.
Joshi, Sanket J.
Al-Wahaibi, Yahya M.
Al-Bemani, Ali S.
Al-Bahry, Saif N.
Al-Maqbali, Dua'a
Banat, Ibrahim M.
[J]. FRONTIERS IN MICROBIOLOGY, 2015, 6
[9] Measurement of local gas holdup in bubble columns via a non-isokinetic withdrawal method
García-Salas, S
Orozco-Alvarez, C
Porter, RM
Thalasso, F
[J]. CHEMICAL ENGINEERING SCIENCE, 2005, 60 (24) : 6929 - 6938
[10] Relationships between hydrodynamics and rheology of flocculating yeast suspensions in a high-cell-density airlift bioreactor
Klein, J
Maia, J
Vicente, AA
Domingues, L
Teixeira, JA
Jurascík, M
[J]. BIOTECHNOLOGY AND BIOENGINEERING, 2005, 89 (04) : 393 - 399

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