Gliflozins in the Management of Cardiovascular Disease

被引:142
作者
Braunwald, Eugene [1 ,2 ,3 ]
机构
[1] Brigham & Womens Hosp, Div Cardiovasc Med, TIMI Study Grp, Hale Bldg Transformat Med,Suite 7022,60 Fenwood Rd, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Div Cardiovasc Med, TIMI Study Grp, Boston, MA USA
[3] Harvard Med Sch, Dept Med, Boston, MA USA
关键词
COTRANSPORTER; 2; INHIBITORS; REDUCED EJECTION FRACTION; SGLT2; HEART-FAILURE; DIABETES-MELLITUS; KIDNEY-DISEASE; EMPAGLIFLOZIN; DEATH; NA+; DAPAGLIFLOZIN;
D O I
10.1056/NEJMra2115011
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Gliflozins in Cardiac and Renal DiseaseGliflozins - sodium-glucose cotransporter 2 inhibitors - lower blood glucose and glycated hemoglobin in patients with type 2 diabetes without causing hypoglycemia. The agents also improve cardiac function in patients who have heart failure with or without type 2 diabetes and improve renal function, with few adverse effects.
引用
收藏
页码:2024 / 2034
页数:11
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