Pulmonary hypertension and its management in patients undergoing non-cardiac surgery

被引:93
作者
Pilkington, S. A. [1 ]
Taboada, D. [2 ]
Martinez, G. [3 ]
机构
[1] Queen Elizabeth Hosp NHS Fdn Trust, Dept Anaesthesia, Kings Lynn, England
[2] Queen Elizabeth Hosp NHS Fdn Trust, Pulm Vasc Dis Unit, Kings Lynn, England
[3] Papworth Hosp NHS Fdn Trust, Dept Anaesthesia, Cambridge, England
关键词
INTRAOPERATIVE TRANSESOPHAGEAL ECHOCARDIOGRAPHY; RIGHT-VENTRICULAR DYSFUNCTION; ARTERIAL-HYPERTENSION; PREGNANCY OUTCOMES; VASCULAR-RESISTANCE; DOUBLE-BLIND; ANESTHESIA; THERAPY; HEART; PROSTACYCLIN;
D O I
10.1111/anae.12831
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Pulmonary hypertension is a complex disorder of the pulmonary vasculature that leads to increased peri-operative morbidity and mortality. Non-cardiac surgery constitutes a significant risk in patients with pulmonary hypertension. The management of right ventricular failure is inherently challenging and fraught with life-threatening consequences. A thorough understanding of the pathophysiology, the severity of the disease and its treatment modalities is required to deliver optimal peri-operative care. This review provides an evidence-based overview of the definition, classification, pathophysiology, diagnosis and treatment of pulmonary hypertension and focuses on the peri-operative management and treatment of pulmonary hypertensive crises in a non-cardiac setting.
引用
收藏
页码:56 / 70
页数:15
相关论文
共 80 条
[1]   Basic Science of Pulmonary Arterial Hypertension for Clinicians New Concepts and Experimental Therapies [J].
Archer, Stephen L. ;
Weir, E. Kenneth ;
Wilkins, Martin R. .
CIRCULATION, 2010, 121 (18) :2045-U175
[2]   A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension [J].
Barst, RJ ;
Rubin, LJ ;
Long, WA ;
McGoon, MD ;
Rich, S ;
Badesch, DB ;
Groves, BM ;
Tapson, VF ;
Bourge, RC ;
Brundage, BH ;
Koerner, SK ;
Langleben, D ;
Keller, CA ;
Murali, S ;
Uretsky, BF ;
Clayton, LM ;
Jobsis, MM ;
Blackburn, SD ;
Shortino, D ;
Crow, JW .
NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (05) :296-301
[3]  
Bassily-Marcus AM, 2012, PULMONARY MED, V2012, P1
[4]   Has there been any progress made on pregnancy outcomes among women with pulmonary arterial hypertension? [J].
Bedard, Elisabeth ;
Dimopoulos, Konstantinos ;
Gatzoulis, Michael A. .
EUROPEAN HEART JOURNAL, 2009, 30 (03) :256-265
[5]   An Evaluation of Long-term Survival From Time of Diagnosis in Pulmonary Arterial Hypertension From the REVEAL Registry [J].
Benza, Raymond L. ;
Miller, Dave P. ;
Barst, Robyn J. ;
Badesch, David B. ;
Frost, Adaani E. ;
McGoon, Michael D. .
CHEST, 2012, 142 (02) :448-456
[6]   Pulmonary arterial hypertension - Pathophysiology and anesthetic approach [J].
Blaise, G ;
Langleben, D ;
Hubert, B .
ANESTHESIOLOGY, 2003, 99 (06) :1415-1432
[7]   Oxidative stress in severe pulmonary hypertension [J].
Bowers, R ;
Cool, C ;
Murphy, RC ;
Tuder, RM ;
Hopken, MW ;
Flores, SC ;
Voelkel, NF .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2004, 169 (06) :764-769
[8]   Anesthesia for Noncardiac Surgery in Adults with Congenital Heart Disease [J].
Cannesson, Maxime ;
Earing, Michael G. ;
Collange, Vincent ;
Kersten, Judy R. .
ANESTHESIOLOGY, 2009, 111 (02) :432-440
[9]   Haemodynamic evaluation of pulmonary hypertension [J].
Chemla, D ;
Castelain, V ;
Hervé, P ;
Lecarpentier, Y ;
Brimioulle, S .
EUROPEAN RESPIRATORY JOURNAL, 2002, 20 (05) :1314-1331
[10]   SURVIVAL IN PATIENTS WITH PRIMARY PULMONARY-HYPERTENSION - RESULTS FROM A NATIONAL PROSPECTIVE REGISTRY [J].
DALONZO, GE ;
BARST, RJ ;
AYRES, SM ;
BERGOFSKY, EH ;
BRUNDAGE, BH ;
DETRE, KM ;
FISHMAN, AP ;
GOLDRING, RM ;
GROVES, BM ;
KERNIS, JT ;
LEVY, PS ;
PIETRA, GG ;
REID, LM ;
REEVES, JT ;
RICH, S ;
VREIM, CE ;
WILLIAMS, GW ;
WU, M .
ANNALS OF INTERNAL MEDICINE, 1991, 115 (05) :343-349