Heart Rate and Blood Pressure: "Connecting the Dots" in Epidemiology and Pathophysiology

被引：6

作者：

Kouvas, Nikos ^{[1
]}

Tsioufis, Costas ^{[1
]}

Vogiatzakis, Nikolaos ^{[1
]}

Sanidas, Elias ^{[2
]}

Konstantinidis, Dimitrios ^{[1
]}

Kintis, Konstantinos ^{[1
]}

Dimitriadis, Kyriakos ^{[1
]}

Kakosaiou, Zoi ^{[1
]}

Tsioufis, Panagiotis ^{[1
]}

Kouremeti, Mairi ^{[1
]}

Katsiki, Niki ^{[3
]}

Tousoulis, Dimitrios ^{[1
]}

机构：

[1] Univ Athens, Hippokrat Hosp, Med Sch, Cardiol Clin 1, 114 Vas Sofias Ave, Athens 11527, Greece

[2] Laikon Gen Hosp, Dept Cardiol, Athens, Greece

[3] Aristotle Univ Thessaloniki, Propedeut Dept Internal Med 2, Med Sch, Hippokrat Hosp, Thessaloniki, Greece

来源：

ANGIOLOGY | 2018年 / 69卷 / 08期

关键词：

heart rate; blood pressure; hypertension; CARDIOVASCULAR-DISEASE; ALL-CAUSE; ANTIHYPERTENSIVE DRUGS; HYPERTENSIVE PATIENTS; AORTIC STIFFNESS; EUROPEAN-SOCIETY; PROGNOSTIC VALUE; BETA-BLOCKERS; ORGAN DAMAGE; MORTALITY;

D O I：

10.1177/0003319717746524

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

There is robust evidence from epidemiological and clinical studies showing that elevated heart rate (HR) constitutes a powerful predictor of morbidity and mortality in patients with hypertension, underlining the significance of HR measurement in them. Autonomous nervous system dysfunction and atherosclerosis are important features in the pathogenesis of the untoward events. However, the relationship between HR and blood pressure (BP) is complex and differs depending on the type of BP measurement which is considered. This differentiation implicates complex physiological mechanisms and is of clinical importance regarding the divergent effect of the different types of antihypertensive agents on these parameters. The aim of this review is to summarize the current evidence on the relationship between HR and BP based on epidemiological, clinical, and experimental studies.

引用

页码：660 / 665

页数：6

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