Evaluation of Antifouling Potential and Ecotoxicity of Secondary Metabolites Derived from Red Algae of the Genus Laurencia

被引：16

作者：

Protopapa, Maria ^{[1
]}

Kotsiri, Manto ^{[1
]}

Mouratidis, Sofoklis ^{[1
]}

Roussis, Vassilios ^{[2
]}

Ioannou, Efstathia ^{[2
]}

Dedos, Skarlatos G. ^{[1
]}

机构：

[1] Univ Athens, Dept Biol, Athens 15784, Greece

[2] Univ Athens, Dept Pharm, Sect Pharmacognosy & Chem Nat Prod, Athens 15771, Greece

来源：

MARINE DRUGS | 2019年 / 17卷 / 11期

关键词：

Laurencia; red algae; biofouling; ecotoxicity; Amphibalanus amphitrite; barnacles; perforenol; MARINE NATURAL-PRODUCTS; CHEMICAL DEFENSE; SETTLEMENT; BACTERIA; SURFACE; LOCALIZATION; INHIBITION; TRANSPORT; TOXICITY; PROTEIN;

D O I：

10.3390/md17110646

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Red algae of the genus Laurencia are known to biosynthesize and secrete an immense variety of secondary metabolites possessing a spectrum of biological activities against bacteria, invertebrates and mammalian cell lines. Following a rigorous cross-species screening process, herein we report the antifouling potential of 25 secondary metabolites derived from species of the genus Laurencia, as well as the thorough evaluation of the ecotoxicity of selected metabolites against non-target marine arthropods and vertebrate cell lines. A number of these secondary metabolites exhibited potent antifouling activity and performed well in all screening tests. Our results show that perforenol (9) possesses similar antifouling activity with that already described for bromosphaerol, which is used herein as a benchmark.

引用

收藏

页数：15

相关论文

共 50 条

[21] In Vivo and in Vitro Anti-Inflammatory Activity of Neorogioltriol, a New Diterpene Extracted from the Red Algae Laurencia glandulifera [J].

Chatter, Rim ;

Ben Othman, Rym ;

Rabhi, Sameh ;

Kladi, Maria ;

Tarhouni, Safa ;

Vagias, Constantinos ;

Roussis, Vassilios ;

Guizani-Tabbane, Lamia ;

Kharrat, Riadh .

MARINE DRUGS, 2011, 9 (07) :1293-1306

[22] Antifouling Activity of Secondary Metabolites Isolated from Chinese Marine Organisms [J].

Yong-Xin Li ;

Hui-Xian Wu ;

Ying Xu ;

Chang-Lun Shao ;

Chang-Yun Wang ;

Pei-Yuan Qian .

Marine Biotechnology, 2013, 15 :552-558

[23] Biosynthesis of cyclic bromo-ethers, derived from red algae [J].

Ishihara, J ;

Murai, A .

JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 2001, 59 (12) :1181-1189

[24] Secondary Metabolites Isolated from Chilean Marine Algae: A Review [J].

Arrieche, Dioni ;

Carrasco, Hector ;

Olea, Andres F. ;

Espinoza, Luis ;

San-Martin, Aurelio ;

Taborga, Lautaro .

MARINE DRUGS, 2022, 20 (05)

[25] Evaluation of Oxasqualenoids from the Red Alga Laurencia viridis against Acanthamoeba [J].

Lorenzo-Morales, Jacob ;

Diaz-Marrero, Ana R. ;

Cen-Pacheco, Francisco ;

Sifaoui, Ines ;

Reyes-Batlle, Maria ;

Souto, Maria L. ;

Hernandez Daranas, Antonio ;

Pinero, Jose E. ;

Fernandez, Jose J. .

MARINE DRUGS, 2019, 17 (07)

[26] Natural Products from Red Algal Genus Laurencia as Potential Inhibitors of RdRp and nsp15 Enzymes of SARS-CoV-2: An In Silico Perspective [J].

Pokharkar, Omkar ;

Anumolu, Harshavardhan ;

Zyryanov, Grigory V. ;

Tsurkan, Mikhail V. .

MICROBIOLOGY RESEARCH, 2023, 14 (03) :1020-1048

[27] Traffic of Secondary Metabolites to Cell Surface in the Red Alga Laurencia dendroidea Depends on a Two-Step Transport by the Cytoskeleton [J].

Reis, Vanessa M. ;

Oliveira, Louisi S. ;

Passos, Raoni M. F. ;

Viana, Nathan B. ;

Mermelstein, Claudia ;

Sant'Anna, Celso ;

Pereira, Renato C. ;

Paradas, Wladimir C. ;

Thompson, Fabiano L. ;

Amado-Filho, Gilberto M. ;

Salgado, Leonardo T. .

PLOS ONE, 2013, 8 (05)

[28] Bactericide, Antioxidant and Cytotoxic Activities from Marine Algae of Genus Laurencia Collected in Baja California Sur, Mexico [J].

Garcia-Davis, Sara ;

Murillo-Alvarez, Ivan ;

Munoz-Ochoa, Mauricio ;

Carranza-Torres, Edith ;

Garza-Padron, Ruth ;

Morales-Rubio, Eufemia ;

Viveros-Valdez, Ezequiel .

INTERNATIONAL JOURNAL OF PHARMACOLOGY, 2018, 14 (03) :391-396

[29] Potential of secondary metabolites from soil-derived actinomycetes as juvenile hormone disruptor and insecticides [J].

Kim, Jong-Hoon ;

Choi, Jae Young ;

Park, Dong Hwan ;

Je, Yeon Ho .

JOURNAL OF ASIA-PACIFIC ENTOMOLOGY, 2024, 27 (03)

[30] Phytochemical screening, antioxidant potential, and cytotoxic effects of different extracts of red algae (Laurencia snyderiae) on HT29 cells [J].

Karimzadeh, Katayoon ;

Zahmatkesh, Asgar .

RESEARCH IN PHARMACEUTICAL SCIENCES, 2021, 16 (04) :400-413

← 1 2 3 4 5 →