Centralized Pan-Middle East Survey on the Undertreatment of Hypercholesterolemia: Results From the CEPHEUS Study in Arabian Gulf Countries

被引:23
作者
Arafah, Mohamed [1 ]
Al-Hinai, Ali T. [2 ]
Al Mahmeed, Wael [3 ]
Al-Rasadi, Khalid [4 ]
Al Tamimi, Omer [5 ]
Al Herz, Shorook [6 ]
Al Anazi, Faisal [7 ]
Al Nemer, Khalid [8 ]
Metwally, Othman [9 ]
Alkhadra, Akram [10 ]
Fakhry, Mohammed [10 ]
Elghetany, Hossam [11 ]
Medani, Abdel Razak [12 ]
Yusufali, Afzal Hussein [12 ]
Al Jassim, Obaid [12 ]
Al Hallaq, Omar [13 ]
Baslaib, Fahad Omar Ahmed S. [14 ]
Alawadhi, Mahmoud [15 ]
Amin, Haitham [16 ]
Al-Hashmi, Khamis [2 ]
Shehab, Abdullah [17 ]
机构
[1] King Khalid Univ Hosp, Riyadh 11472, Saudi Arabia
[2] Sultan Qaboos Univ, Coll Med & Hlth Sci, Muscat, Oman
[3] Sheikh Khalifa Med City, Abu Dhabi, U Arab Emirates
[4] Sultan Qaboos Univ Hosp, Muscat, Oman
[5] Hamad Med Corp, Doha, Qatar
[6] King Fahad Natl Guard Hosp, Riyadh, Saudi Arabia
[7] Minist Hlth, Riyadh, Saudi Arabia
[8] Secur Force Hosp, Riyadh, Saudi Arabia
[9] King Fahad Gen Hosp, Jeddah, Saudi Arabia
[10] Univ Khobar, King Fahad Hosp, Khobar, Saudi Arabia
[11] Soliman Fakieh Hosp, Jeddah, Saudi Arabia
[12] Dubai Hosp, Dubai, U Arab Emirates
[13] Amer Hosp, Dubai, U Arab Emirates
[14] Rashid Hosp, Dubai, U Arab Emirates
[15] Al Amiri Hosp, Kuwait, Kuwait
[16] Bahrain Def Force Hosp, Riffa, Bahrain
[17] UAE Univ, Al Ain, U Arab Emirates
关键词
hypercholesterolemia; lipids; low-density lipoprotein; cardiovascular; coronary; guidelines; Arabian Gulf countries; DENSITY-LIPOPROTEIN-CHOLESTEROL; CARDIOVASCULAR-DISEASE PREVENTION; CORONARY-HEART-DISEASE; LIPID-LOWERING-THERAPY; CLINICAL-PRACTICE; EUROPEAN GUIDELINES; MYOCARDIAL-INFARCTION; EVENTS; MEN; PRAVASTATIN;
D O I
10.1177/0003319713512414
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
The Centralized pan-Middle East Survey on the undertreatment of hypercholesterolemia (CEPHEUS) survey evaluated the attainment of low-density lipoprotein cholesterol (LDL-C) goals among patients on lipid-lowering drugs (LLDs) according to the updated National Cholesterol Education Program (NCEP)-Adult Treatment Panel (ATP-III) guideline. The survey was conducted in 6 Arabian Gulf countries. Patients aged >= 18 years on LLDs for at least >= 3 months (stable medication for >= 6 weeks) were recruited. Fasting blood samples were collected at a single visit. In this survey, 5276 (58.2% male) patients were included in the final analysis. The LDL-C goal was attained in 91.1% of low-risk, 52.7% of high-risk, and 32.0% in very-high-risk categories. Goal attainment was directly related to female gender, age < 40 years, history of diabetes, and family history of cardiovascular disease. The results of this survey highlight the suboptimal management of hypercholesterolemia across Arabian Gulf countries.
引用
收藏
页码:919 / 926
页数:8
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