(R,R,R)-2,5-diaminocylohexanecarboxylic acid, a building block for water-soluble, helix-forming β-peptides

被引:42
作者
Appella, DH [1 ]
LePlae, PR [1 ]
Raguse, TL [1 ]
Gellman, SH [1 ]
机构
[1] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA
关键词
D O I
10.1021/jo000277h
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:4766 / 4769
页数:4
相关论文
共 31 条
[1]  
Abele S, 1998, HELV CHIM ACTA, V81, P2141, DOI 10.1002/(SICI)1522-2675(19981216)81:12<2141::AID-HLCA2141>3.0.CO
[2]  
2-5
[3]   Synthesis and characterization of trans-2-aminocyclohexanecarboxylic acid oligomers:: An unnatural helical secondary structure and implications for β-peptide tertiary structure [J].
Appella, DH ;
Christianson, LA ;
Karle, IL ;
Powell, DR ;
Gellman, SH .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (26) :6206-6212
[4]   Formation of short, stable helices in aqueous solution by β-amino acid hexamers [J].
Appella, DH ;
Barchi, JJ ;
Durell, SR ;
Gellman, SH .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (10) :2309-2310
[5]   beta-peptide foldamers: Robust Helix formation in a new family of beta-amino acid oligomers [J].
Appella, DH ;
Christianson, LA ;
Karle, IL ;
Powell, DR ;
Gellman, SH .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (51) :13071-13072
[6]   Solution conformations of helix-forming β-amino acid homooligomers [J].
Barchi, JJ ;
Huang, XL ;
Appella, DH ;
Christianson, LA ;
Durell, SR ;
Gellman, SH .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (12) :2711-2718
[7]   Bioinspired polymeric materials: in-between proteins and plastics [J].
Barron, AE ;
Zuckermann, RN .
CURRENT OPINION IN CHEMICAL BIOLOGY, 1999, 3 (06) :681-687
[8]  
COLE DC, 1994, TETRAHEDRON, V50, P9517
[9]   Aziridine 2-carboxylate ester mediated asymmetric synthesis of alpha-alkyl beta-amino acids [J].
Davis, FA ;
Reddy, GV ;
Liang, CH .
TETRAHEDRON LETTERS, 1997, 38 (29) :5139-5142
[10]   The twists and turns of β-peptides [J].
DeGrado, WF ;
Schneider, JP ;
Hamuro, Y .
JOURNAL OF PEPTIDE RESEARCH, 1999, 54 (03) :206-217