Malignant transformation of renal angiomyolipoma

被引：31

作者：

Takahashi, N ^{[1
]}

Kitahara, R ^{[1
]}

Hishimoto, Y ^{[1
]}

Ohguro, A ^{[1
]}

Hashimoto, Y ^{[1
]}

Suzuki, T ^{[1
]}

机构：

[1] Hirosaki Univ, Sch Med, Dept Urol, Hirosaki, Aomori 0368563, Japan

来源：

INTERNATIONAL JOURNAL OF UROLOGY | 2003年 / 10卷 / 05期

关键词：

HMB-45; malignant transformation; renal angiomyolipoma; TUBEROUS SCLEROSIS; EPITHELIOID ANGIOMYOLIPOMA; CARCINOMA;

D O I：

10.1046/j.1442-2042.2003.00620.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

In the present paper, two cases of malignant transformation of renal angiomyolipoma without tuberous sclerosis are reported. Pathological examination revealed that, in both cases, in addition to the areas affected by typical angiomyolipoma, there were areas that contained elevated numbers of perivascular epithelioid cells with prominent nuclear pleomorphism. Immunohistochemical examination revealed that both cases were negative for keratin and epithelial membrane antigen, but were positive for the melanogenesis-related marker HMB-45. Metastatic diseases appeared 40 months after radical nephrectomy in the first case and 18 months in the second case.

引用

页码：271 / 273

页数：3

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