LOPHTOR: a convenient flow-based photochemical reactor

被引：54

作者：

Vasudevan, Anil ^{[1
]}

Villamil, Clara ^{[1
]}

Trumbull, Jonathan ^{[1
]}

Olson, Jeff ^{[1
]}

Sutherland, David ^{[1
]}

Pan, Jeff ^{[1
]}

Djuric, Stevan ^{[1
]}

机构：

[1] Abbott Labs, Abbott Pk, IL 60064 USA

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 31期

关键词：

ORGANIC-SYNTHESIS; CHEMISTRY; OPTIMIZATION; SPACE;

D O I：

10.1016/j.tetlet.2010.05.119

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A flow-through photochemical reactor which enables facile control of irradiation time, temperature, and wavelength with minimal manual intervention is described. A series of intramolecular [2+2] enone cycloadditions were performed in this reactor in excellent yield and significantly shorter reaction time than conventional batch processes. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：4007 / 4009

页数：3

共 16 条

[1]

Ahmed-Omer B., 2008, Microreactors in Organic Synthesis and Catalysis, P122

[2]

Albini A., 1997, Drugs - Photochemistry and Photostability, P1

[3] SYNTHETIC APPLICATIONS OF INTRAMOLECULAR ENONE OLEFIN PHOTOCYCLOADDITIONS [J].