Acute bilateral mydriasis associated with anti-GQ1b antibody

被引：12

作者：

Fleury, V. ^{[1
]}

Aqallal, A. ^{[2
]}

Lagrange, E. ^{[1
]}

Besson, G. ^{[1
]}

Caudie, C. ^{[2
]}

机构：

[1] Grenoble Univ Hosp, Dept Neurol, Grenoble, France

[2] Neurol & Neurosurg Hosp, Immunol & Neuroimmunol Dept, Lyon, France

来源：

JOURNAL OF CLINICAL NEUROSCIENCE | 2010年 / 17卷 / 04期

关键词：

Anti-GQ1b antibody; Miller Fisher syndrome; Mydriasis; IGG ANTIBODY; OPHTHALMOPLEGIA;

D O I：

10.1016/j.jocn.2009.06.030

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Miller Fisher syndrome (MFS) is an autoimmune neuropathy characterized by external ophthalmoplegia, ataxia and areflexia. Mydriasis is present in 35% of typical MFS. We report five patients with acute bilateral mydriasis, either isolated or associated with external ophthalmoplegia for which the presumed diagnosis of "atypical MFS" was confirmed by the positivity of anti-GQ1b antibodies. Acute bilateral mydriasis raises important differential diagnoses in clinical practice. This report demonstrates that acute mydriasis can be autoimmune mediated and that anti-GQ1b antibodies are useful to confirm the diagnosis in unexplained cases. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：514 / 515

页数：2

共 8 条

[1] Acute ophthalmoplegia with pupillary areflexia associated with anti-GQ1b antibody [J].