The ins and outs of p53

被引：68

作者：

Vousden, KH ^{[1
]}

Vande Woude, GF

机构：

[1] NCI, Frederick, MD 21702 USA

[2] Van Andel Res Inst, Grand Rapids, MI 49503 USA

来源：

NATURE CELL BIOLOGY | 2000年 / 2卷 / 10期

关键词：

D O I：

10.1038/35036427

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Moving proteins between cellular locations is proving to be a tightly regulated process, and provides an important mechanism for controlling protein function. The tumour-suppressor protein p53 has been shown to use microtubules to aid nuclear localization, a finding that raises interesting questions about the action of microtubule-disrupting chemotherapeutic drugs.

引用

收藏

页码：E178 / E180

页数：3

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