Synthesis, Antibacterial and Antifungal Evaluation of Novel 3-(5-Phenyl[1,3,4]oxadiazol-2-yl]-3,4-dihydro-2H-benzo[e][1,3]oxazines

被引：1

作者：

Vasu, N. ^{[1
]}

Goud, B. Bharath Kumar ^{[1
]}

Kumari, Y. Bharathi ^{[2
]}

Rao, B. Pulla ^{[2
]}

机构：

[1] Suven Life Sci Ltd, Hyderabad 500055, Andhra Pradesh, India

[2] Jawaharlal Nehru Technol Univ, Dept Chem, Hyderabad 500072, Andhra Pradesh, India

来源：

ASIAN JOURNAL OF CHEMISTRY | 2014年 / 26卷 / 14期

关键词：

1,3,4-Oxadiazoles; 1,3-Oxazines; Antimicrobial activity; Nematicidal activity; 1,3,4-OXADIAZOLE DERIVATIVES; ANTIINFLAMMATORY ACTIVITY; AGENTS;

D O I：

10.14233/ajchem.2014.16030

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Various novel 3-(5-phenyl[1,3,4]oxadiazol-2-yl]-3,4-dihydro-2H-benzo[e][1,3]oxazines (5a-g) have been synthesized from 5-phenyl[ 1,3,4]oxadiazol-2-ylamine (1) and different salicylaldehydes (2a-g) as starting materials and 2-[(5-phenyl[1,3,4]oxadiazol-2ylimino) methyl] phenols (3a-g) and 2-[(5-phenyl[1,3,4]oxadiazol-2-ylamino)methyl] phenols (4a-g) as intermediates. The newly synthesized compounds after structural confirmation were used to screen their antibacterial, antifungal and nematicidal activities and some of these compounds have been found as potential antimicrobial agents.

引用

页码：4145 / 4148

页数：4

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