Kinetics and mass transfer of organic liquid-phase reactions in the presence of a sparingly soluble solid phase

被引：4

作者：

Tirronen, E

Salmi, T ^{[1
]}

Lehtonen, J

Vuori, A

Grönfors, O

Kaljula, K

机构：

[1] Abo Akad, Proc Chem Grp, Lab Ind Chem, FIN-20500 Turku, Finland

[2] Kemira Agro Oy, Espoo Res Ctr, FIN-22071 Espoo, Finland

[3] Neste Engn, FIN-06191 Porvoo, Finland

来源：

ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2000年 / 4卷 / 05期

关键词：

D O I：

10.1021/op0000172

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Several organic liquid-phase reactions are carried out in the presence of a sparingly soluble reactive solid phase which is gradually dissolved during the course of the reaction. The presence of the reactive solid phase complicates the treatment of kinetic data, since the overall reaction rate is influenced by the solubility equilibrium and mass transfer rate of the solid compound. A mathematical model has been derived for an organic reaction system with one reactive solid compound. The modelling concept was applied on a linear multistep reaction system, Claisen condensation, The solubility of the solid compound was measured with batch experiments carried out under nonreactive conditions, and the kinetic parameters for the reaction system were determined from the data obtained by semibatch experiments. Model simulations clarified the behavior of the sparingly soluble reactive compound in the process, indicating that the rate equations describe well the experimental kinetic data.

引用

页码：323 / 332

页数：10