Metal- and Solvent-Free Synthesis ofTetrahydrobenzo[c]carbazolones through NaI-Catalyzed Formal [4+2] Annulation

被引：5

作者：

Fang, Fang ^{[1
,2
]}

Zheng, Haolin ^{[1
]}

Mao, Guojiang ^{[3
]}

Chen, Shanping ^{[1
]}

Deng, Guo-Jun ^{[1
]}

机构：

[1] Xiangtan Univ, Coll Chem,Minist Educ, Key Lab Environmentally Friendly Chem & Applicat, Key Lab Green Organ Synth & Applicat Hunan Prov, Xiangtan 411105, Peoples R China

[2] Hunan City Univ, Coll Mat & Chem Engn, Yiyang 413000, Peoples R China

[3] Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Henan, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2022年 / 87卷 / 09期

基金：

中国国家自然科学基金;

关键词：

C-H ACTIVATION; ONE-POT SYNTHESIS; FUNCTIONALIZED CARBAZOLES; SUBSTITUTED CARBAZOLES; FACILE ACCESS; INDOLES; ACID; EFFICIENT; ALKYNES; CYCLIZATION;

D O I：

10.1021/acs.joc.2c00315

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel strategy for the preparation of functionalcarbazoles through NaI-catalyzed formal [4 + 2] annulation of 2-(indol-3-yl)cyclohexanones and alkynes/alkenes has been devel-oped. The present approach started from easily available rawmaterials and provided a variety of tetrahydrobenzo[c]carbazolonesin satisfactory yields under metal- and solvent-free conditions.Furthermore, the products could be further transformed intostructurally valuable carbazole-based conjugated derivatives

引用

页码：6052 / 6063

页数：12

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