Synthesis of dibenzo[a,c]carbazoles from 2-(2-halophenyl)-indoles and iodobenzenes via palladium-catalyzed dual C-H functionalization

被引：19
|
作者：
Wu, Lijun [1 ]
Deng, Guobo [1 ]
Liang, Yun [1 ]
机构：
[1] Hunan Normal Univ, Key Lab Assembly & Applicat Organ Funct Mol, Changsha 410081, Hunan, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2017年 / 15卷 / 32期
基金：
中国国家自然科学基金;
关键词：
POTENTIAL ANTICANCER AGENTS; DIELS-ALDER REACTION; BIOLOGICAL EVALUATION; CARBAZOLE ALKALOIDS; DERIVATIVES; ROUTE; ANNULATION; ARYLATION; INDOLES; CASCADE;
D O I：
10.1039/c7ob01638g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient palladium-catalyzed strategy for the synthesis of dibenzo[a,c] carbazole derivatives has been developed. In the presence of Pd(OAc)(2), 2-(2-halophenyl)-indoles and iodobenzenes proceeded smoothly to obtain the corresponding dibenzo[a,c] carbazoles in moderate to good yields. This methodology constructs two new C-C bonds via a palladium-catalyzed dual C-H functionalization.
引用
收藏
页码：6808 / 6812
页数：5
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