Evaluation of the effect of time on the distribution of zinc oxide nanoparticles in tissues of rats and mice: a systematic review

被引:28
作者
Chen, Aijie [1 ]
Feng, Xiaoli [1 ]
Sun, Ting [2 ]
Zhang, Yanli [1 ]
An, Shengli [3 ]
Shao, Longquan [1 ]
机构
[1] Southern Med Univ, Nanfang Hosp, 1838 Guangzhou Ave North, Guangzhou, Guangdong, Peoples R China
[2] Jinan Univ, Med Ctr Stomatol, Affiliated Hosp 1, 613 Huangpu Ave West, Guangzhou, Guangdong, Peoples R China
[3] Southern Med Univ, Sch Publ Hlth & Trop Med, Guangdong Prov Key Lab Trop Dis Res, 1838 Guangzhou Ave North, Guangzhou, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
nanoparticles; zinc compounds; II-VI semiconductors; wide band gap semiconductors; biological tissues; lung; liver; brain; kidney; toxicology; biology computing; time effect; zinc oxide nanoparticles distribution; rat tissues; mice tissues; PubMed; Embase; SpringerLink; Scopus; Science Direct; Cochrane; CNKI; Wanfang; vip databases; screening; data extraction; quality assessment; Zn content; time; 24; h; ZnO; SINGLE INTRAVENOUS-INJECTION; ZNO NANOPARTICLES; OXIDATIVE STRESS; ACUTE TOXICITY; DRUG-DELIVERY; TOXICOLOGICAL IMPACT; GROWTH-PERFORMANCE; MOUSE-LIVER; DNA-DAMAGE; IN-VITRO;
D O I
10.1049/iet-nbt.2015.0006
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
To evaluate the time effect on the distribution of zinc oxide nanoparticles (ZnO NPs) in tissues from rats and mice, a search on the PubMed, Embase, SpringerLink, Scopus, Science Direct, Cochrane, CNKI, Wanfang, and vip databases up to September 2014 was performed, followed by screening, data extraction, and quality assessment. Thirteen studies were included. At 24 h, Zn content was mainly distributed in the liver, kidney, and lung. At 7 days, Zn content was mainly distributed in the liver, kidney, lung, and brain. ZnO NPs are readily deposited in tissues. Furthermore, as time increases, Zn content decreases in the liver and kidney, but increases in the brain.
引用
收藏
页码:97 / 106
页数:10
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