Applications of FT-IR Spectrophotometry in Cancer Diagnostics

被引:61
作者
Bunaciu, Andrei A. [1 ]
Vu Dang Hoang [2 ]
Aboul-Enein, Hassan Y. [3 ]
机构
[1] SCIENT Res Ctr Instrumental Anal SC CROMATEC PLUS, Bucharest, Romania
[2] Hanoi Univ Pharm, Dept Analyt Chem & Toxicol, Hanoi, Vietnam
[3] Natl Res Ctr, Pharmaceut & Drug Ind Res Div, Pharmaceut & Med Chem Dept, Cairo 12311, Egypt
关键词
clinical diagnosis; early detection of cancer; biomedical analysis; FT-IR spectroscopy; TRANSFORM-INFRARED-SPECTROSCOPY; LUNG-CANCER; PROSTATE TISSUE; CERVICAL-CANCER; BREAST-CANCER; CELLS; SERUM; MICROSPECTROSCOPY; CLASSIFICATION; BIOSPECTROSCOPY;
D O I
10.1080/10408347.2014.904733
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
This review provides a brief background to the application of infrared spectroscopy, including Fourier transform-infrared spectroscopy, in biological fluids. It is not meant to be complete or exhaustive but to provide the reader with sufficient background for selected applications in cancer diagnostics. Fourier transform-infrared spectroscopy (FT-IR) is a fast and nondestructive analytical method. The infrared spectrum of a mixture serves as the basis to quantitate its constituents, and a number of common clinical chemistry tests have proven to be feasible using this approach. This review focuses on biomedical FT-IR applications, published in the period 2009-2013, used for early detection of cancer through qualitative and quantitative analysis.
引用
收藏
页码:156 / 165
页数:10
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