Ste12 and Ste12-Like Proteins, Fungal Transcription Factors Regulating Development and Pathogenicity

被引：114

作者：

Hoi, Joanne Wong Sak ^{[2
]}

Dumas, Bernard ^{[1
,2
]}

机构：

[1] Univ Toulouse 3, CNRS, UMR 5546, F-31326 Castanet Tolosan, France

[2] CNRS, F-31326 Castanet Tolosan, France

来源：

EUKARYOTIC CELL | 2010年 / 9卷 / 04期

关键词：

CRYPTOCOCCUS-NEOFORMANS; PSEUDOHYPHAE FORMATION; SIGNALING SPECIFICITY; CANDIDA-ALBICANS; INVASIVE GROWTH; KINASE PATHWAY; YEAST; HOMOLOG; GENE; VIRULENCE;

D O I：

10.1128/EC.00333-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Ste12 and Ste12-like proteins are transcription factors found exclusively in the fungal kingdom. In the yeast model Saccharomyces cerevisiae, where the first member was identified, Ste12p was shown to regulate mating and invasive/pseudohyphal growth. In recent literature, there have been several reports of Ste12-like factors in multiple fungal systems, yeasts or filamentous fungi, with saprophytic or parasitic life-styles. In all these models, Ste12 and Ste12-like factors are involved in the regulation of fungal development and pathogenicity. In this review, we discuss the features, the regulation, and the role of Ste12 and Ste12-like factors by highlighting the similarities and dissimilarities that occur within this group.

引用

页码：480 / 485

页数：6

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