Subphthalocyanines: addressing water-solubility, nano-encapsulation, and activation for optical imaging of B16 melanoma cells

被引：34

作者：

Bernhard, Yann ^{[1
]}

Winckler, Pascale ^{[2
]}

Chassagnon, Remi ^{[3
]}

Richard, Philippe ^{[1
]}

Gigot, Elodie ^{[1
]}

Perrier-Cornet, Jean-Marie ^{[2
]}

Decreau, Richard A. ^{[1
]}

机构：

[1] Univ Bourgogne, CNRS, UMR 6302, Inst Chim Mol, F-21078 Dijon, France

[2] Univ Bourgogne, Dimacell Imaging Ressource Ctr, AgroSup Dijon, UMR A PAM 02 102, F-21000 Dijon, France

[3] Univ Bourgogne, UMR CNRS 6303, Lab Interdisciplinaire Carnot Bourgogne, F-21078 Dijon, France

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 90期

关键词：

SUBSTITUTED SUBPHTHALOCYANINES; SOLUBLE SUBPHTHALOCYANINES; PHOTODYNAMIC ACTIVITIES; PHTHALOCYANINES; DERIVATIVES; MELANOCYTES; EFFICACY; THERAPY;

D O I：

10.1039/c4cc05503a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Water-soluble disulfonato-subphthalocyanines (SubPcs) or hydrophobic nano-encapsulated SubPcs are efficient probes for the fluorescence imaging of cells. 20 nm large liposomes (TEM and DLS) incorporated about 13% SubPc. Moreover, some of these fluorophores were found to be pH activatable.

引用

页码：13975 / 13978

页数：4

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