TB-HIV co-infection in the Netherlands: estimating prevalence and under-reporting in national registration databases using a capture-recapture analysis

被引：9

作者：

van Leth, Frank ^{[1
]}

Evenblij, Kirsten ^{[2
]}

Wit, Ferdinand ^{[1
,3
]}

Kiers, Albert ^{[4
]}

Sprenger, Herman ^{[5
]}

Verhagen, Maurits ^{[6
]}

Hillebregt, Mariska ^{[7
]}

Kalisvaart, Nico ^{[8
]}

Schimmel, Henrieke ^{[9
]}

Verbon, Annelies ^{[10
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Amsterdam Inst Global Hlth & Dev, Dept Global Hlth, Meibergdreef 9, NL-1105 AZ Amsterdam, Netherlands

[2] Amsterdam Inst Global Hlth & Dev, Amsterdam, Netherlands

[3] Univ Amsterdam, Acad Med Ctr, Dept Internal Med, Meibergdreef 9, NL-1105 AZ Amsterdam, Netherlands

[4] Municipal Publ Hlth Serv Fryslan, Leeuwarden, Netherlands

[5] Univ Groningen, Univ Med Ctr Groningen, Infect Dis Serv, Dept Internal Med, Groningen, Netherlands

[6] Municipal Publ Hlth Serv Limburg Noord, Venlo, Netherlands

[7] Stichting HIV Monitoring, Amsterdam, Netherlands

[8] KNCV TB Fdn, The Hague, Netherlands

[9] Natl Inst Publ Hlth & Environm, NL-3720 BA Bilthoven, Netherlands

[10] Erasmus MC, Div Infect Dis, Dept Internal med, Rotterdam, Netherlands

来源：

JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH | 2016年 / 70卷 / 06期

关键词：

TUBERCULOSIS; EPIDEMIOLOGY; DISEASE; POLICY; RISK;

D O I：

10.1136/jech-2015-206680

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background Knowledge of the HIV status in patients with tuberculosis (TB) and vice versa is crucial for proper individual patient management, while knowledge of the prevalence of co-infection guides preventive and therapeutic strategies. The aim of the study was to assess if national disease databases on TB and HIV are adequate sources to provide this information. Methods A two way capture-recapture analysis to assess the completeness of the registers, and to obtain the prevalence of TB-HIV co-infection in the Netherlands in the years 2002-2012. Results HIV testing was performed in less than 50% of the patients with TB. Of the 932 TB-HIV infected patients, just 293 (31.4%) were registered in both registers. Under-reporting of TB-HIV co-infection ranged from 50% to 70% in the national TB register, and from 31% to 37% in the HIV database. Prevalence of TB-HIV co-infection in the Netherlands in 2012 was 7.1% (95% CI 6.0% to 8.3%), which was more than double of the prevalence estimated from the national TB database. Conclusions TB-HIV co-infection is markedly under-reported in national disease databases. There is an urgent need for improved registration and preferably a routine data exchange between the two surveillance systems.

引用

页码：556 / 560

页数：5