Use of isavuconazole in a patient with voriconazole-induced QTc prolongation

被引：20
作者：
Trang, Tracy P. [1 ]
Hanretty, Alexandra M. [2 ]
Langelier, Charles [3 ]
Yang, Katherine [4 ]
机构：
[1] Kaiser Permanente, Inpatient Pharm, Downey, CA USA
[2] Temple Univ, Sch Pharm, Dept Pharm, Philadelphia, PA 19122 USA
[3] Univ Calif San Francisco, Div Infect Dis, San Francisco, CA 94143 USA
[4] Univ Calif San Francisco, San Francisco Sch Pharm, Dept Clin Pharm, San Francisco, CA 94143 USA
来源：
TRANSPLANT INFECTIOUS DISEASE | 2017年 / 19卷 / 04期
关键词：
Aspergillus; isavuconazole; QTc; torsades; voriconazole; INTERVAL PROLONGATION; TRANSPLANTATION; IMPACT;
D O I：
10.1111/tid.12712
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A 22-year-old woman with cystic fibrosis developed QTc interval prolongation following lung transplantation in the setting of voriconazole therapy. After the discontinuation of voriconazole and initiation of isavuconazole, her QTc interval normalized. This case highlights the unique property of QTc interval shortening by isavuconazole among the triazole antifungals.
引用
收藏
页数：3
相关论文
共 14 条
  • [1] Voriconazole-induced QT interval prolongation and ventricular tachycardia: A non-concentration-dependent adverse effect
    Alkan, Y
    Haefeli, WE
    Burhenne, J
    Stein, J
    Yaniv, I
    Shalit, I
    [J]. CLINICAL INFECTIOUS DISEASES, 2004, 39 (06) : E49 - E52
  • [2] Astellas Pharma US, 2015, CRES PACK INS
  • [3] Astellas Pharma US. Isavuconazonium NDAs, 2015, IS NDAS 207500 20750
  • [4] Voriconazole-induced QT interval prolongation and torsades de pointes
    Aypar, Ebru
    Kendirli, Tanil
    Tutar, Ercan
    Ciftci, Ergin
    Ince, Erdal
    Ileri, Talia
    Atalay, Semra
    [J]. PEDIATRICS INTERNATIONAL, 2011, 53 (05) : 761 - 763
  • [5] Center for Drug Evaluation and Research, 2015, PHARM TOX NDA REV EV
  • [6] Long-Term Impact of Different Immunosuppressive Drugs on QT and PR Intervals in Renal Transplant Patients
    Ikitimur, Baris
    Cosansu, Kahraman
    Karadag, Bilgehan
    Cakmak, Huseyin Altug
    Avci, Burcak Kilickiran
    Erturk, Emre
    Seyahi, Nurhan
    Ongen, Zeki
    [J]. ANNALS OF NONINVASIVE ELECTROCARDIOLOGY, 2015, 20 (05) : 426 - 432
  • [7] Impact of cytochrome P450 2C19 polymorphisms on the pharmacokinetics of tacrolimus when coadministered with voriconazole
    Imamura, Chiyo K.
    Furihata, Kenichi
    Okamoto, Shinichiro
    Tanigawara, Yusuke
    [J]. JOURNAL OF CLINICAL PHARMACOLOGY, 2016, 56 (04) : 408 - 413
  • [8] Knirsch CA, 2012, NEW ENGL J MED, V367, P772, DOI [10.1056/NEJMoa1003833, 10.1056/NEJMc1207269]
  • [9] Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): a phase 3, randomised-controlled, non-inferiority trial
    Maertens, Johan A.
    Raad, Issam I.
    Marr, Kieren A.
    Patterson, Thomas F.
    Kontoyiannis, Dimitrios P.
    Cornely, Oliver A.
    Bow, Eric J.
    Rahav, Galia
    Neofytos, Dionysios
    Aoun, Mickael
    Baddley, John W.
    Giladi, Michael
    Heinz, Werner J.
    Herbrecht, Raoul
    Hope, William
    Karthaus, Meinolf
    Lee, Dong-Gun
    Lortholary, Olivier
    Morrison, Vicki A.
    Oren, Ilana
    Selleslag, Dominik
    Shoham, Shmuel
    Thompson, George R., III
    Lee, Misun
    Maher, Rochelle M.
    Schmitt-Hoffmann, Anne-Hortense
    Zeiher, Bernhardt
    Ullmann, Andrew J.
    [J]. LANCET, 2016, 387 (10020) : 760 - 769
  • [10] Cardiac QTc interval characteristics before and after hematopoietic stem cell transplantation: an analysis of 995 consecutive patients at a single center
    Miller, W. P.
    Shanley, R.
    Dorostkar, P.
    [J]. BONE MARROW TRANSPLANTATION, 2015, 50 (07) : 954 - 960
12