Synthesis of Nucleoside Phosphate and Phosphonate Prodrugs

被引：485

作者：

Pradere, Ugo ^{[1
,2
]}

Garnier-Amblard, Ethel C. ^{[3
]}

Coats, Steven J. ^{[3
]}

Amblard, Franck ^{[1
,2
]}

Schinazi, Raymond F. ^{[1
,2
]}

机构：

[1] Emory Univ, Sch Med, Dept Pediat, Ctr AIDS Res,Lab Biochem Pharmacol, Atlanta, GA 30322 USA

[2] Vet Affairs Med Ctr, Atlanta, GA 30322 USA

[3] RFS Pharma LLC, Tucker, GA 30084 USA

来源：

CHEMICAL REVIEWS | 2014年 / 114卷 / 18期

关键词：

HEPATITIS-C VIRUS; ANTI-HIV ACTIVITY; POSSIBLE ANTIVIRAL AGENTS; PHOSPHORAMIDATE PROTIDE TECHNOLOGY; REPLICATION IN-VITRO; ACYCLOVIR DIPHOSPHATE DIMYRISTOYLGLYCEROL; PRELIMINARY BIOLOGICAL EVALUATION; ARYL PHOSPHOTRIESTER DERIVATIVES; LIPOPHILIC NUCLEOTIDE PRODRUGS; TOXIC LIPONUCLEOTIDE ANALOGS;

D O I：

10.1021/cr5002035

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：9154 / 9218

页数：65

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