Post Surgical Non-tuberculous Mycobacterium: A Case Series

被引:4
作者
Mhaske, Ashok N. [1 ]
Mhaske, Shubhangi [2 ]
Harke, Sanjay [3 ]
Jain, Arti [4 ]
Patel, Jaswant [5 ]
Mhaske, Sumedh [6 ]
机构
[1] Peoples Univ, Peoples Coll Med Sci & Res Ctr, Dept Surg, Bhopal, India
[2] Peoples Univ, Peoples Coll Med Sci & Res Ctr, Dept Oral Pathol & Microbiol, Bhopal, India
[3] Mahatma Gandhi Mission MGM Inst Biosci & Technol, Dept Biotechnol, Aurangabad, Maharashtra, India
[4] Peoples Univ, Peoples Coll Med Sci & Res Ctr, Dept Microbiol, Bhopal, India
[5] Peoples Univ, Ctr Sci Res & Dev, Bhopal, India
[6] Govt Med Coll, Dept Med, Aurangabad, Maharashtra, India
关键词
non tuberculous mycobacterium; post-surgical wounds; pcr; genotyping; antibiotic susceptibility; RAPIDLY GROWING MYCOBACTERIA; INFECTION; RESISTANCE;
D O I
10.7759/cureus.24701
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background There has been an increase in non-tuberculous mycobacteria (NTM) infection reports in humans. Surgeons are concerned about the link between them and surgical site infections. As a result, it has been challenging to determine just how common this illness is. A two-year study by the authors examines the occurrence of NTM infections after different surgical procedures. Design and methods Researchers at a tertiary care hospital in central India performed this prospective study over two years. NTM was found in six of the 25 instances of post-surgical wound infections. Ziehl-Neelsen staining, Auramine ORhodamine fluorescence staining, Multiplex Real-Time PCR, and Genotyping were used to identify the species. Results M. fortuitum, M. chelonae and M.kansasii were isolated from discharge in 2 cases each respectively. NTM isolates evaluated for antibiotic susceptibility pattern were all sensitive to Clarithromycin (100%). One case with prolonged healing had to be intervened with amikacin along with clarithromycin. Conclusion NTM is an infection of uncommon nature which can occur following surgical procedures. Identification of these organisms through sensitive techniques and appropriate therapeutic regimen formulation must be done to tackle this growing menace in health care setups.
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页数:6
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